Fig. 8. Snail function in neuroblasts requires the dCtBP co-repressor interaction motif. The schematic shows the protein structure of Snail. The embryos show RNA in situ hybridization for ftz (A-C,E,G) and inscuteable (D,F,H). All the embryos are osp29 mutants, except in A (wild type). (C,D) Embryos expressing a P[snail] transgene in which the N-terminal dCtBP interaction motif is mutated (M1). (E,F) Embryos containing the M2 mutant; (G,H) Embryos containing the M12 double mutant. There is much lower rescue of ftz and inscuteable in the absence of both dCtBP interaction motifs.
