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Fig. 1. The striatal complex at E18.5 in wild types and Gsh2 homozygous mutants. Immunostaining for ISL1 (A,B) delineates the entire striatal complex while SOX1 staining (C,D) selectively marks the olfactory tubercle and portions of the nucleus accumbens (Acc) (i.e. ventral striatum). The Gsh2 mutant displays a significant reduction in size of the striatal complex (B), which is most prominent in the ventral striatum, in particular within the olfactory tubercle (OT) region (B,D). Stm, striatum.





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