
Fig. 4. Gsh1 expression in wild types and Gsh2 mutants. At E16.5, Gsh1 expression in the wild type is confined to the ventralmost VZ corresponding to the former MGE and medialmost LGE (A). In Gsh2-/- embryos at this stage, Gsh1 transcripts are detected at a high level throughout the LGE (B). Arrowheads in A and B indicate the LGE-cortex boundary. At E12.5, wild-type Gsh1 expression is observed in the MGE and medialmost LGE (C). A slight expansion of the Gsh1 expression domain is evident in the Gsh2 mutant at this stage (D).