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Fig. 6. Patch-matrix organization at E18.5 in Gsh1 and Gsh1/2 double homozygous mutants. The Gsh1 mutant striatum appears identical to wild type for DARPP-32 (A), µ-OR (C) and CaBP (E). The Gsh1/2 double mutant striatum is devoid of DARPP-32-positive neurons (C) and no µ-OR patches can be detected (F). Arrowheads in A and C point to patches. Neurons expressing CaBP are detected in the rudimentary double mutant striatum (F). ac, anterior comissure; cc, corpus callosum.





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