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Fig. 7. Conserved repression of crest migration in mouse/chick grafts. (A) DiI-labelled mouse r3 cells transplanted into r4 of the chick generate numerous ncc, which colonise ba2. Ov, otic vesicle. (B) DiI-labelled r4 cells derived from the Hoxb1-lacZ transgenic line and transplanted into r3 of the chick are unable to generate ncc. (C) This is not due to a change in their A-P identity or cell death, as grafted mouse cells continue to strongly express the reporter gene.
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