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Fig. 5. Examples of aberrant vulval development in ku234 mutant L4 hermaphrodites. (A) Wild type. (B) ku234: descendants of P7.p (arrow) have not joined in the main invagination. About 50% of ku234 exhibit this phenotype (non-Vul-abnormal), while the rest have apparently normal vulvae. (C) ku234/s472: descendents of P7.p (arrow) appear non-vulval. About a third of the non-Dpy segregants from ku234 dpy-11/unc-62(s472) unc-46 exhibited this semi-vulvaless phenotype, which is only slightly more severe that the non-Vul-abnormal phenotype in B. The remaining non-Dpy animals were either non-Vul-abnormal or normal. (D) ku234/sDf27: posterior Pn.p cells appear to be generating vulval-like descendants near the tail (arrow). This phenotype was seen only occasionally. As in C, about a third of the non-Dpy segregants of ku234 dpy-11/sDf27 unc-46 exhibited the semi-vulvaless phenotype, while the rest were non-Vul-abnormal or normal.





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