Fig. 12. FGF signaling is required for telencephalic gene expression. As shown in the schematic, the early dorsal blastopore lip (brown) of a stage 10-10⁺ gastrula was sandwiched either between two uninjected stage 9 animal caps (A-C) or animal caps injected with XFGFR-4a (320 pg/blastomere) (blue) in all four animal blastomeres of eight-cell stage embryos (D-F). Conjugates were grown to stage 30/31 and assayed for expression of Xnkx2.1 (A,D), Xemx1 (B,E) or Sox2 (C,F).

Return to article