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Fig. 6. The ADE promotes Xemx1 expression and downregulates Xnkx2.1 expression in explants of DE. (A,B) DE (violet in upper schematic) was explanted from stage 10.5 embryos, cultured to stage 22/23 (A) or 30/31 (B) and assayed for expression of Xemx1 (A) or Xnkx2.1 (B). (C,D) DE (violet in lower schematic) was explanted from stage 10.5 embryos together with the ADE (yellow in lower schematic), grown to stage 22/23 (C) or 30/31 (D), and assayed for expression of Xemx1 (C) or Xnkx2.1 (D).





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