Fig. 7. Dome controls the expression of several follicle cell markers. Immunostaining (in red) of dome mosaic egg chambers using anti-DE-cadherin (A,B), anti-Fas3 (C-F) and anti-Crumbs (G-J) antibodies. (A,B) Confocal sections of two different egg chambers showing reduction of DE-cadherin. Fas3 is normally expressed in polar cells in wild-type egg chambers (C), and becomes overexpressed in dome mutant cells close to the anterior (E) or posterior (F) polar cells. dome mutant clones generated away from the poles also accumulate Fas3 (D). Mutant clones have been outlined (dotted lines in A,B,D,E,F and solid bar in G-J). Anterior is to the left.

Return to article