
Fig. 6. JAK pathway activity is required in the soma. Somatic mosaics of Stat92Ej6C8 show the same chamber fusion phenotype as the hop heteroallelic ovaries. Clones are marked by the loss of
-Myc (green, mutant cells outlined) and Fas III staining is shown in red. (A) In an ovariole with nearly all mutant follicle cells in the vitellarium (brackets), multiple cysts are fused into a single egg (posterior). Approximately 8 stalk cells can be identified (arrow), all of which are wild type for Stat92E. (B) In a late stage fused chamber, the mutant clone is in the middle of the fusion, presumably corresponding to the anterior terminus of the older chamber and the posterior terminus of the younger chamber. (C) Consistent with the alteration of fate seen in hop mutant heteroallelic combinations, clones of hopc111 mutant cells (lack of green GFP) express the polar cell marker PZ80 (red).