Fig. 9. Ratios of retinal cell types induced by misexpression of bHLH genes and Pax6. Ratios with s.e. of amacrine cells (A, calbindin+), bipolar cells (B, PKC+), horizontal cells (C, calbindin+), rods (D, rhodopsin+) and Müller glial cells (E, GS+) are the average of at least three independent experiments. Co-expression of Pax6 and Math3 significantly increases the population of amacrine and horizontal cells while that of Pax6 and NeuroD only increases the population of amacrine cells. By contrast, co-expression of Pax6 and Mash1 does not increase the number of any mature cells.
