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Fig. 4. Analysis of cell death in Wnt1-/-, En1-/- and Fgf8 MHB KO mutants. (A-C) Dorsal views of control and mutant embryos of the genotypes indicated, stained in whole mount with NBS. Schematic diagrams and arrowheads are as described in Fig. 3. In C, note that the midbrain appears partially truncated in the En1-/- embryo, mostly deleted in the Wnt1-/- embryo, and completely absent in the Fgf8 MHB KO embryo (indicated by half pink, half green arrowhead). *, partial deletion; Fb, forebrain; Hb, hindbrain; Mb, midbrain.





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