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Fig. 7. Ftz modulates Runt-dependent activation and repression of wg and
en. Expression of wg (A-D) and en (E-H) in response
to different perturbations in Runt and Ftz activity. (A,E) Response of these
two genes to transient elimination of run in a temperature-shifted
run[YP17] embryo. (B,F) Response to NGT-driven Ftz. These
embryos are from a mating of homozygous NGT40 females to homozygous
UAS-ftz[261] males. (C,G) NGT-driven co-expression of Runt
and Ftz blocks wg expression, while producing a pair-rule pattern of
en expression. (D) Response of wg to NGT-driven
co-expression of Runt and Opa. This embryo is from a mating of females
homozygous for both NGT40 and NGTA to males homozygous for
the UAS-runt[13] and UAS-opa[14] transgenes. This
combination results in a slp1 pattern similar to the embryos in
Fig. 4F,H. (H) Response of
en to NGT-driven Runt in embryos that are also homozygous
for the ftz[11] mutation. This embryo is from the same cross used to
generate the embryo in Fig.
5C.
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