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Fig. 4. Xbh1 enhances the RGC-inducing ability of atonal-related
genes. (A,B) Retinas lipofected with Xath3+GFP or
Xath3+Xbh1+GFP. (C,D) Percentage of RGCs (C) or
photoreceptors (D) in retinae lipofected with GFP+pCS2
vector, or with GFP in combination with Xbh1, Xath5, Xath5+Xbh1,
Xath3, or Xath3+Xbh1. The percent representation of each cell
type was calculated as the average±s.e.m. Counted cells were:
n=2625 cells from six retinae for GFP; n=2908 cells
from six retinae for Xbh1; n=1087 cells from 10 retinae for
Xath5; n=1375 cells from 11 retinae for Xath5+Xbh1;
n=2018 from seven retinae for Xath3; and n=1406
from eight retinae for Xath3+Xbh1. Significant differences have been
determined by one-way analysis of variance (ANOVA) with the Tukey-Kramer
Multiple Comparisons Test as a post-test. Black asterisks represent
significant differences (**P<0.01,
***P<0.001).
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