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Fig. 4. Trajectories of representative cells contributing to distinct neural
subdivisions. (A) Distinct trajectories of cells that contributed to neural
and non-neural tissues displayed on an embryo model in dorsal view from stage
13 (black dots) to stage 15 (blue dots), and then to stage 16+ (red dots).
Trajectories of the cells are color-coded according to the later contributing
neural subdivisions, as in Fig.
3: red, telencephalon; green, retina; orange, mesencephalon; blue,
rhombencephalon; white, spinal cord; yellow, placode and neural crest derived
tissue; light blue, epidermis. (B-H) Trajectories of ten randomly selected
cells (with exception of telencephalon, five) that later contributed to
different neural subdivisions: (B) telencephalon; (C) retina; (D)
diencephalon; (E) mesencephalon; (F) rhombencephalon; (G) spinal cord; (H)
tissue of placode and neural crest origin. Colored dots in black, blue, red
and yellow indicate cell positions at stage 13 (25% epiboly), stage 15 (50%
epiboly), stage 16+ (90% epiboly) and stage 24, respectively. Figures in the
bottom right-hand corner indicate the average distance (µm) of migration
among the cell groups from stage 13 to stage 15 (upper) and from stage 15 to
stage 16+ (lower). Scale bar: 200 µm.
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