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Fig. 7. Pax6 expression and establishment of neural compartments. (A,C,E) Pax6 expression and (B,D,F) corresponding regions of the computer graphics model. Broken lines surround cells of prospective retina. (A,B) At stage 16+ (22 hpf), Pax6 expression is first detected in a pair of lateral domains that include future lateral retinal cells, while prospective retinal cells in the middle do not express Pax6 yet. (C-F) After stage 16++ (23 hpf), Pax6 is now strongly expressed in the entire prospective retina, diencephalic cells and r1-r2 region of rhombencephalon, and moderately in the remaining part of the prospective rhombencephalon and spinal cord.





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