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Fig. 3. Match of the model results to the experimental data of Rosoff et al. (Rosoff et al., 2004). Parameters used are shown in Table 1, with KD=3 nM. (A) Response as a function of gradient steepness for an absolute concentration of 1 nM. (B) Response as a function of absolute concentration for a gradient steepness of 0.2%. The solid red curves show the data originally plotted by Rosoff et al. (Rosoff et al., 2004), whereas the dashed red curves show the revised experimental data that is obtained if all of the explants from the 0.2% gradient/1 nM condition are averaged together (see text).





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