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Fig. 4. Rescue of the DTC migration defect by the DTC-specific expression of active SRC-1. (A-F) Shown are Nomarski images of the posterior gonad lobe at the young adult stage in the src-1(cj293) mutant (A), the src-1(cj293) mutant expressing src-1 (B) or src-1K290M (C) under the src-1 promoter, the src-1(cj293) mutant expressing src-1 (D) or src-1K290M (E) under the lag-2 promoter, and the src-1(cj293) mutant expressing src-1 under the myo-3 promoter (F). Arrows show the migration pattern of the DTCs. Scale bar: 20 µm. (G) Percentages of worms with DTC migration defects in their anterior or posterior lobe are indicated. For each transgene, two independent lines were scored; similar results were obtained. The total numbers of worm observed (n) are also indicated.





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