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Fig. 7. Defects in the migration of the QR neuroblast and its descendants in the src-1(cj293) mutant. (A) Schematic representation of the AVM and ALM neuronal cells that originate from the QR neuroblast and the PVM descendant of the QL neuroblast. (B-E) The GFP signals produced from mec-7::gfp in wild-type worms (B) and the src-1(cj293) mutant (D) were visualized by epifluorescence. The merged GFP and DIC images are shown in C and E. Scale bar: 20 µm. (F) The genetic interaction of the aberrant AVM phenotype in the src-1(cj293) mutant with the ced-5/-12 mutations. The final positions of AVM and PVM in the wild-type and indicated mutant worms were scored according to their relative distance from the stationary Vn.a and Vn.p cells shown on the x-axis.





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