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Fig. 3. Angioblast migration to the midline. (A-E) Transverse sections visualized
for GFP (green), fibronectin (blue) and ß-catenin (red). The GFP (green)
and fibronectin (blue) signals of the outlined areas are also shown
separately. The sections shown are at the level of the 6th (A,B), 10th (C) and
14th (D,E) somite. White arrowheads in A and B mark angioblasts that are still
residing within the LPM and that will migrate during a second wave. White
arrowheads in C show fibronectin deposition around a single endothelial cell
within the vascular cord. Over the span of 14 hours, the angioblasts migrate
to the midline where they aggregate to form a vascular cord that subsequently
lumenizes. NT, neural tube; NC, notochord; DA, dorsal aorta; PCV, posterior
cardinal vein.
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