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Fig. 2. Effect of loss-of-function USP on the expression of proneural and
neurogenic genes in the wing margin [usp2 clones in a
Minute (RpS52) background]. Absence of GFP (green) marks
usp2 tissue. (A,A') Wing disc from a late feeding
larva. Expression of the ac-lacZ reporter is not affected by loss of
USP function. (B,B') The neur reporter A101 in a disc from an
early wandering larva is precociously expressed in the absence of USP
function. (C,C') Senseless (SENS) is expressed precociously in the
mutant clone in a disc from an early wandering larva. Note the accumulation of
SENS in the mutant SOPs. In wild-type tissue low levels are detected
anteriorly. (D) Diagram gives the orientation of the disc with the area
depicted in A-C. Arrowheads indicate estimated intersection of the A/P
boundary with the margin. A'-C' show the expression of the
different markers.
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