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Fig. 4. BR function is required for sens expression in the wing margin. (A,A') A large npr3 clone in a Minute (Rp5S) background. SENS protein (A') is not detected in the npr3 clone (GFP negative area, A) in the wing margin, but is expressed normally in the region along the third vein [see Murray et al. (Murray et al., 1984) for nomenclature of these sensilla]. Image is a composite of projections of the dorsal epithelium only. (B-F) Misexpression of br isoforms and their effect on SENS expression in the wing margin. (B) Normal pattern of SENS expression in control disc. (C) dpp-GAL4 driving UAS-br-Z1 leads to ectopic SENS expression and early SOP differentiation (arrow). (D) ddp-GAL4 driving UAS-br-Z2 leads to ectopic SENS expression (arrow). However SENS has not accumulated in the SOPs in the area of ectopic SENS expression. (E) Ectopic SENS is expressed in a wing disc where dpp-GAL4 drives UAS-br-Z3 but does not lead to precocious accumulation of SENS in the SOPs. (F) Misexpressing br-Z4 using the dpp-GAL4 driver does not induce ectopic SENS expression. Asterisks in all panels indicate the approximate axis of dpp-GAL4 expression.





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