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Fig. 5. Methylation analysis at three DMRs of the Cdkn1c locus in the
absence of Lsh. The methylation status was determined as outlined in
Fig. 4. The arrow indicates the
transcription start site. Each row corresponds to an individual sequenced
strand of DNA, and each circle represents a CpG on the strand, red circles and
blue circles indicate methylated and unmethylated sites, respectively.
Maternal (M) and paternal (P) alleles were distinguished by a DNA polymorphism
in the DMR sequences (129/Czech: 5' DMR Cdkn1c (ICG5) 34012
T/G; KvDMR1: ICG8a 101803 A/G and ICG8b 103181 G/C).
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