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Fig. 7. Expression of nk2.2a and ntn1 is expanded dorsally in the midbrain and hindbrain neural tube of mol-/- embryos, but is reduced in smu-/- embryos. Lateral views of brains of wild-type (A,D,G,J), mol-/- (B,E,H,K), smu-/- (C,F,I,L) and mol-/-;syu-/- double mutant (M,N) embryos and mol-/- embryos treated with cyclopamine (O) (cpm) analysed for expression of genes indicated bottom right. Arrows indicate ectopic dorsal expression of ntn1 (B,E) and nk2.2a (H) in mol-/- embryos. cpm, cyclopamine; e, endoderm; fp, floorplate; MFP, medial floorplate.





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