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Fig. 3. Signal transduction in dally dlp mutants expressing exogenous
Wingless. (A) Lawn phenotype of an embryo lacking maternal and zygotic
dally and dlp, as shown in
Fig. 2E. (B) Naked cuticle is
induced along the ventral region by expression of GFP-Wingless under the
control of sim-gal4 in dally dlp-deficient embryos [as used by
Desbordes and Sanson (Desbordes and
Sanson, 2003)]. This shows that signal transduction can take place
in the absence of the glypicans if sufficient Wingless expression is
sustained.