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Fig. 1. Dally and Dlp are required for the proper distribution of extracellular Wg.
All wing discs are oriented dorsal top-right, anterior top-left. All mutant
clones are marked by the absence of GFP and outlined by broken lines.
(A-C') Extracellular Wg staining in discs bearing large clones mutant
for dally. Extracellular Wg is significantly reduced in the clones in
a cell non-autonomous manner. The yellow arrows indicate the wild-type cells
that have reduced extracellular Wg level. (D-E') Extracellular Wg
staining in discs bearing large clones mutant for dlp. Within the
clones, extracellular Wg is reduced outside of a zone that is 7-10 cell
diameters wide and centered at the DV boundary. (F-G') Extracellular Wg
staining in discs bearing large clones mutant for both dally and
dlp. Extracellular Wg level is greatly reduced in these clones, and
the reduction is stronger than that of dally or dlp
alone.
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