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Fig. 4. Pattern of nuclear cortical migration from late telophase at cycle 9 to early interphase of cycle 10. A projection of time-lapse recordings collected with 10-second intervals reveals the patterns. Genotypes of the embryos are labeled above images; posterior (A,B,D) and anterior (C) parts of the embryos are shown. Arrows (A-D) trace the direction of nuclear movement over 120 seconds. Note the straight movement in A, the meandering pattern in B, and the curved movement in C and D. Insets (a1-a3, b1-b3, c1-c3 and d1-d3) are images with 30-second intervals during cortical migration. Images in a1, b1, c1 and d1 begin at slightly different time-points, because most nuclei move in and out of focal planes during the recording. Scale bars: in D, 40 µm for A-D; in d3, ~10 µm for all insets.





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