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Fig. 7. The abscisic acid (ABA) signalling pathway that controls the regulation
of flowering time. (A) At low ABA concentrations, FCA and FY
interact and together prevent the accumulation of FLC mRNA. FLC is a
potent inhibitor of flowering, as several pathways converge on it to block the
expression of the floral integration gene SOC1 by directly binding to
its promoter (Hepworth et al.,
2002). (B) ABA binds to the C-terminal part of FCA, close
to its interaction site with FY, disrupting the association of these two
proteins in vitro and leading to the accumulation of FLC in vivo,
which delays flowering. Transcription of SOC1 only occurs in plants
with low FLC levels; additional cues are required for the transition
to flowering.
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