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Figure 1


Fig. 1. Isolation and characterization of K2 and N55 alleles. Genotypes are indicated in each panel. FRT, FRT42D. (A) The unmodified GMR-hid ey-FLP (GheF) eye-ablation phenotype. (B,C) K2 (B) and N55 (C) alleles are moderate suppressors of the GheF-eye phenotype. (D-F) Adult eyes of ey-FLP-induced mosaics of wild-type (D), and K2 (E) and N55 (F). K2 and N55 mosaic eyes lack mutant clones (marked by the absence of red pigment) and are overgrown. (G-I) Eye-antennal discs from third instar larvae of K2 (H) and N55 mosaics (I) are overgrown and disorganized compared with wild type (G). Scale bar: 100 µm. (J-L) Non-autonomous suppression of GMR-hidw- in K2 and N55 mosaics. (J) Control: in ark mosaics, largely ark mutant clones (marked by an absence of eye pigment) suppress GMR-hidw-. (K,L) In K2 (K) and N55 (L) mosaics, the suppression of GMR-hidw- is mediated by wild-type tissue (red pigment). K2 and N55 clones do not contribute.





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