spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 1


Fig. 1. Range of Hh activation in the wing disc. (A, part a) A schematic of Drosophila wing imaginal disc staining [adapted from Callejo et al. (Callejo et al, 2006)]. Anterior (A) is to the left. (a,b) Hh-producing cells in the posterior (P) compartment are shown in green. Ptc (red) appears as a stripe that abuts the AP boundary. (A, part c) Expression of relevant target genes. Engrailed (En, blue) and Patched (Ptc, pink) are high threshold targets. Decapentaplegic (Dpp, yellow) and Collier (not shown) are medium threshold targets, and Iroquois (Iro, orange) is a low threshold target. (A, part d) A graphic representation of target activation represented by the colours above, as a function of local Hh concentration. The vertical line represents the AP compartment boundary. (B) Cross-section of a wing imaginal disc. The wing pouch is covered by an epithelium called the peripodial membrane (PM). The lumen between the disc proper cells and the PM is the peripodial space (PS). Here, the PM is highlighted with horse radish peroxidase (HRP) (micrograph courtesy of Laurence Dubois, Centre de Biologie du Développement, Toulouse, France).





Right arrow Return to article