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Figure 8


Fig. 8. DFer interactions with the JNK pathway. (A) Stage 13 wild-type embryos express dpp in leading edge cells (arrowhead) and in the midgut. (B,C) In Src42Amyri embryos (B), dpp expression in leading edge cells (arrowheads) is slightly reduced and expression is almost lost in Src42Amyri;dfer{Delta}1 double mutants (C). (D-G) dpp (E) and puc-lacZ (G) expression in leading edge cells of dfergof mutants (arrowheads) is comparable to wild type (D,F). (H,I) Phosphotyrosine staining in dfergof/dfergof (H) and UAS-puc, dfergof/dfergof (I) embryos. (I) Expression of the JNK inhibitor Puc with dfergof serving as the GAL4 driver, rescues the dorsal open phenotype of dfergof mutants.





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