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Fig. 2. Perlecan is required for cell membrane polarity. trol
clones show defects in the distribution of various cell polarity markers
(filled arrowheads indicate normal; open arrowheads disrupted protein
localization). (A,B) Baz (red) is generally enriched and
expanded into the cytoplasm. (C) Patj (red) is not affected by the loss
of Pcan. (D) Apical localization of Crb (red) is frequently reduced.
(E,F) Arm (red) expression is slightly elevated and expanded to
all cell membrane. (G) Dlg (red) is strongly reduced. A'-G' show red
channels only. Clones are marked by the loss of GFP and outlined by broken
lines. Nuclei of follicle cells in ectopic positions are marked with a circle.
Green, GFP; blue, DNA.