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Figure 5


Fig. 5. Socs5-/- mice exhibit accelerated mammary gland development. (A) Whole mounts and H&E-stained sections of inguinal mammary glands from wild-type (WT) and Socs5-/- mice at day 10 and 15 of gestation. (B) The number of alveoli was scored in H&E images from wild-type and Socs5-/- mice at 40x magnification and the area of the fat pad was measured using ImageJ software. The number of alveoli/mm2 was calculated and the percentage relative to wild-type was plotted. (C) Whole mounts and H&E staining of inguinal mammary glands from NOD and NOD-SCID mice at day 5 of gestation. (D) The number of alveoli/mm2 from wild-type, NOD, NOD-SCID, Stat6-/- and IL-4-/-/IL-13-/- mice at day 5 of gestation were plotted on a histogram for comparison.





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