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Figure 3


Fig. 3. SoxN acts downstream of Der- and Wg-pathway activities to direct denticle formation. (A) Cuticle of a wg null mutant larva. (B) Cuticle phenotype of a wg;SoxNU6-35 double-mutant larva; notice that removal of SoxN function largely rescues the wg mutant phenotype. (C-E) Removal of SoxN function rescues the pan mutant phenotype. (C) pan2 mutant cuticle. (D) pan2;SoxNU6-35/+ cuticle. (E) pan2;SoxNU6-35 cuticle. (F) Cuticle of an scaGal4-UAS-EgfrAct larva; note the ectopic denticles posterior to the wild-type row-6 denticles (indicated by arrows). (G) Cuticle of an scaGal4-UAS-EgfrAct;SoxNGA1192 larva; note that ectopic denticle formation is largely suppressed.





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