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Figure 4


Fig. 4. Impaired cell movement in the endoderm of Mixl1GFP/GFP mutant embryos. (A,B) The displacement of DiI-labeled endoderm (yellow because of overlaying of red dye color on the green fluorescence) in Mixl1+/GFP (A) and Mixl1GFP/GFP (B) mutant embryos after 1-, 6-, 12- and 24-hours of in vitro culture. (C,C') Summary of the distribution of DiI-labeled endodermal cells along the anterior-posterior axis of the embryos and in the posterior yolk sac 24 hours after labeling. Each bar represents the pattern of distribution of labeled cells in a single representative embryo after the endoderm overlying the anterior (C) or the posterior (C') region of the primitive streak was painted.





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