|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 5. Allocation of the endoderm to the dorsal and ventral cell population of
the embryonic foregut. (A,B) DiI labeling of the endoderm
overlying the anterior end of the primitive streak in mid-streak (A) and mid-
to late-streak (B) embryos (as staged by the distal extension of the
GFP-expression domain), followed by visualization of the labeled cells at 0
hour (merged GFP and DiI, left images), 12 hours (DiI only, middle images) and
24 hours (top right images, DiI only; bottom right images, merged GFP and DiI)
of in vitro development. (C) The allocation and the path of
displacement of lateral (green) and medial (dark blue and light blue)
populations of the anterior endoderm at the mid-streak and mid- to late-streak
stages of gastrulation. The diagrams show the trajectories of these two
populations of anterior endoderm in the normal (left panels) and the
flattened-disc (right panels) configurations of the embryo
(Tam and Gad, 2004).
(D,D') The spatial correlation of medial and lateral
divisions of the anterior endoderm of the late-bud-stage embryo (D, lateral
view showing Sox17 expression in the anterior endoderm) and the
resultant dorsal (roof) and prospective ventral (floor) regions of the foregut
portal of the early-somite-stage embryo (D', transverse histological
section).
|
