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Fig. 7. Skin localization of differentiation and proliferation markers in
control and K14-Gata3-/- skin. (A-D) Normal
staining of the late-stage differentiation marker loricrin at P1 (A,B) and 5
months (C,D). (E,F) Normal staining of the differentiation
marker K10 at P4. (G,H) K10 expression at P26; note the
cyst-like HFs in K14-Gata3-/-. (I-M)
Double-labelling of K10 (red) and K6 (green) at P11 (I-K) and at 5 months
(L,M). There are clearly separated expression domains in the wt (I), but in
K14-Gata3-/- K6 expression extends more distally (J); the
arrow in K indicates a double-labelled (yellow) cell present in the
K14-Gata3-/-. Scale bar in A: 200 µm for A-H; 150 µm
for I,J,L,M; 10 µm for K.