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Fig. 8. Stage-dependent requirements for Fgf. Embryos were treated with DMSO
(control) or DMSO plus SU5402 for the indicated time intervals. (A-H)
Expression of atoh1a in control and SU5402-treated embryos at 18 hpf
(A,B) and 24 hpf (E,F), and expression of atoh1b in control and
SU5402-treated embryos at 18 hpf (C,D) and 24 hpf (G,H). (I,J)
Expression of atoh1a at 22 hpf in atoh1b morphants treated
with DMSO (I) and DMSO and SU5402 (J). (K,L) Pax2 staining of
hair cells at 30 hpf in embryos treated with DMSO (K) or DMSO and SU5402 (L).
*, treatment for K, L from 18-24 hpf. All images are dorsolateral
views with anterior to the left. Black arrowheads indicate otic expression.
White arrowheads indicate sensory epithelia. Scale bar: 30 µm.
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