spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Cortical and ventral patterning is preserved in Bmpr1a;Bmpr1b mutant mice. RNA in situ hybridization on E10.5 coronal sections. (A-D) The domains of expression for Lhx2 (A,B) and Foxg1 (C,D) are unchanged in the mutant and remain excluded from the dorsomedial area (arrowheads in A-D). (E-H) Fgf8 expression is absent from the most anterior region along the rostral midline (E,F), but is maintained ventrally, as seen in more posterior sections (G,H). (I-L) The ventromedial markers Nkx2.1 (I,J) and Gli1 (K,L) are expressed in the mutant, suggesting that ventral cell fate is unaffected and that SHH signaling is active. Scale bars: 275 µm.





Right arrow Return to article