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Fig. 8. The ability to inhibit neural markers by activated Smad2 attenuates
during gastrulation. Treatment of Xenopus embryos expressing
GR-Smad2 with DEX at different stages during gastrulation showed that
activated GR-Smad2 lost its neural inhibitory activity by the end of
gastrulation, at which stages it also failed to induce mesoderm in the neural
plate. All the embryos were viewed from the dorsal side with the anterior to
the left.