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Fig. 4. Microarray and RT-PCR analyses of gene expression in isolated
seminiferous tubules from XX/Sry and XY W/Wv testes.
(A,B) Microarray expression analysis showing the top 20 genes
that were (A) downregulated and (B) up-regulated in XX/Sry testes. The fold
change represents the difference in the expression level in seminiferous
tubules between XX/Sry and XY W/Wv testes; fold change in
parentheses showing the difference in expression level in whole testis.
(C) RT-PCR analysis of genes selected from the top-20 genes that were
up- and down-regulated in XX/Sry seminiferous tubules.