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Fig. 7. Fgfr2^cn prostates responded only weakly to androgen replenishment. (A) Gross tissue appearance of dorsolateral prostates from Fgfr2^cn and control mice 2 weeks after castration or uncastrated mice at the same age. (B) HE staining of dlp dissected from the mice 2 weeks after castration (0 day) and at the indicated days after the androgen replenishment. (C) Sections were immunostained with anti-PCNA antibodies to reveal the proliferating cells. Inserts: high-magnification views of the same tissue. (D) The mean percentage of PCNA-positive cells in regenerating prostates was calculated from three samples. Data represents means of triplicate samples. CN, Fgfr2^cn mice; F/F, Fgfr2^flox homozygous mice.

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