TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro

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				S. Hanley and L. Rosenberg Transforming Growth Factor {beta} Is a Critical Regulator of Adult Human Islet Plasticity Mol. Endocrinol., June 1, 2007; 21(6): 1467 - 1477. [Abstract] [Full Text] [PDF]

				L. C. Murtaugh Pancreas and beta-cell development: from the actual to the possible Development, February 1, 2007; 134(3): 427 - 438. [Abstract] [Full Text] [PDF]

				D. M. Simeone, L. Zhang, M. K. Treutelaar, L. Zhang, K. Graziano, C. D. Logsdon, and C. F. Burant Islet hypertrophy following pancreatic disruption of Smad4 signaling Am J Physiol Endocrinol Metab, December 1, 2006; 291(6): E1305 - E1316. [Abstract] [Full Text] [PDF]

				H. Ijichi, A. Chytil, A. E. Gorska, M. E. Aakre, Y. Fujitani, S. Fujitani, C. V.E. Wright, and H. L. Moses Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. Genes & Dev., November 15, 2006; 20(22): 3147 - 3160. [Abstract] [Full Text] [PDF]

				L. C. Murtaugh, A. C. Law, Y. Dor, and D. A. Melton {beta}-Catenin is essential for pancreatic acinar but not islet development Development, November 1, 2005; 132(21): 4663 - 4674. [Abstract] [Full Text] [PDF]

				B. Neve, M. E. Fernandez-Zapico, V. Ashkenazi-Katalan, C. Dina, Y. H. Hamid, E. Joly, E. Vaillant, Y. Benmezroua, E. Durand, N. Bakaher, et al. From The Cover: Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function PNAS, March 29, 2005; 102(13): 4807 - 4812. [Abstract] [Full Text] [PDF]

				E. B. Harmon, A. A. Apelqvist, N. G. Smart, X. Gu, D. H. Osborne, and S. K. Kim GDF11 modulates NGN3+ islet progenitor cell number and promotes {beta}-cell differentiation in pancreas development Development, December 15, 2004; 131(24): 6163 - 6174. [Abstract] [Full Text] [PDF]

				K.-H. Yew, K. L. Prasadan, B. L. Preuett, M. J. Hembree, C. R. McFall, C. L. Benjes, A. R. Crowley, S. L. Sharp, Z. Li, S. S. Tulachan, et al. Interplay of Glucagon-Like Peptide-1 and Transforming Growth Factor-{beta} Signaling in Insulin-Positive Differentiation of AR42J Cells Diabetes, November 1, 2004; 53(11): 2824 - 2835. [Abstract] [Full Text] [PDF]

				T. Ogata, L. Li, S. Yamada, Y. Yamamoto, Y. Tanaka, I. Takei, K. Umezawa, and I. Kojima Promotion of {beta}-Cell Differentiation by Conophylline in Fetal and Neonatal Rat Pancreas Diabetes, October 1, 2004; 53(10): 2596 - 2602. [Abstract] [Full Text] [PDF]

				J. M. van Eyll, C. E. Pierreux, F. P. Lemaigre, and G. G. Rousseau Shh-dependent differentiation of intestinal tissue from embryonic pancreas by activin A J. Cell Sci., April 15, 2004; 117(10): 2077 - 2086. [Abstract] [Full Text] [PDF]

				T. Morioka, H. Koyama, H. Yamamura, S. Tanaka, S. Fukumoto, M. Emoto, H. Mizuguchi, T. Hayakawa, I. Kojima, K. Takahashi, et al. Role of H1-Calponin in Pancreatic AR42J Cell Differentiation Into Insulin-Producing Cells Diabetes, March 1, 2003; 52(3): 760 - 766. [Abstract] [Full Text] [PDF]

				L. Rachdi, J.-C. Marie, and R. Scharfmann Role for VPAC2 Receptor-Mediated Signals in Pancreas Development Diabetes, January 1, 2003; 52(1): 85 - 92. [Abstract] [Full Text] [PDF]

				M.-A. Huotari, P. J. Miettinen, J. Palgi, T. Koivisto, J. Ustinov, D. Harari, Y. Yarden, and T. Otonkoski ErbB Signaling Regulates Lineage Determination of Developing Pancreatic Islet Cells in Embryonic Organ Culture Endocrinology, November 1, 2002; 143(11): 4437 - 4446. [Abstract] [Full Text] [PDF]

				Y. Kido, J. Nakae, M. L. Hribal, S. Xuan, A. Efstratiadis, and D. Accili Effects of Mutations in the Insulin-like Growth Factor Signaling System on Embryonic Pancreas Development and beta -Cell Compensation to Insulin Resistance J. Biol. Chem., September 20, 2002; 277(39): 36740 - 36747. [Abstract] [Full Text] [PDF]

				L. Elghazi, C. Cras-Meneur, P. Czernichow, and R. Scharfmann Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation PNAS, March 19, 2002; 99(6): 3884 - 3889. [Abstract] [Full Text] [PDF]

				D. M. Simeone, L. Zhang, K. Graziano, B. Nicke, T. Pham, C. Schaefer, and C. D. Logsdon Smad4 mediates activation of mitogen-activated protein kinases by TGF-{beta} in pancreatic acinar cells Am J Physiol Cell Physiol, July 1, 2001; 281(1): C311 - C319. [Abstract] [Full Text] [PDF]

				L. Zhang, K. Graziano, T. Pham, C. D. Logsdon, and D. M. Simeone Adenovirus-mediated gene transfer of dominant-negative Smad4 blocks TGF-{beta} signaling in pancreatic acinar cells Am J Physiol Gastrointest Liver Physiol, June 1, 2001; 280(6): G1247 - G1253. [Abstract] [Full Text] [PDF]

				L. Lehnert, M. M. Lerch, Y. Hirai, M.-L. Kruse, W. Schmiegel, and H. Kalthoff Autocrine Stimulation of Human Pancreatic Duct-like Development by Soluble Isoforms of Epimorphin In Vitro J. Cell Biol., February 26, 2001; 152(5): 911 - 922. [Abstract] [Full Text] [PDF]

				S. K. Kim and M. Hebrok Intercellular signals regulating pancreas development and function Genes & Dev., January 15, 2001; 15(2): 111 - 127. [Full Text]

				G Deutsch, J Jung, M Zheng, J Lora, and K. Zaret A bipotential precursor population for pancreas and liver within the embryonic endoderm Development, January 3, 2001; 128(6): 871 - 881. [Abstract] [PDF]

				N. Miao, B. Fung, R. Sanchez, J. Lydon, D. Barker, and K. Pang Isolation and Expression of PASK, a Serine/Threonine Kinase, During Rat Embryonic Development, with Special Emphasis on the Pancreas J. Histochem. Cytochem., October 1, 2000; 48(10): 1391 - 1400. [Abstract] [Full Text]

				T. Cook and R. Urrutia TIEG proteins join the Smads as TGF-beta -regulated transcription factors that control pancreatic cell growth Am J Physiol Gastrointest Liver Physiol, April 1, 2000; 278(4): G513 - G521. [Abstract] [Full Text] [PDF]

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