The eed mutation disrupts anterior mesoderm production in mice

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Ang, S.-L. and Rossant, J (1994). HNF-3 is essential for node and notochord formation in mouse development. Cell 78, 561-574.[Medline]

Ang, S.-L., Wierda, A., Wong, D., Stevens, K. A., Cascio, S., Rossant, J. and Zaret, K. S (1993). The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/ forkhead proteins. Development 119, 1301-1315.[Abstract]

Bastian, H. and Gruss, P (1990). A murine even-skipped homologue, Evx 1 , is expressed during early embryogenesis and neurogenesis in a biphasic manner. EMBO J 9, 1839-1852.[Medline]

Beddington, R. S. P (1994). Induction of a second neural axis by the mouse node. Development 120, 613-620.[Abstract]

Beddington, R. S. P. and Smith, J. C (1993). Control of vertebrate gastrulation: inducing signals and responding genes. Curr. Opin. Genet. Dev 3, 655-661.[Medline]

Blum, M., Gaunt, S. J., Cho, K. W. Y., Steinbeisser, H., Blumberg, B., Bittner, D. and De Robertis, E. M (1992). Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell 69, 1097-1106.[Medline]

Chiquoine, A. D (1954). The identification, origin, and migration of the primordial germ cells of the mouse embryo. Anat. Rec 118, 135-146.[Medline]

Cho, K. W. Y., Blumberg, B., Steinbeisseer, H. and De Robertis, E. M (1991). Molecular nature of Spemann's Organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.[Medline]

Conlon, F. L., Lyons, K. M., Takaesu, N., Barth, K. S., Kispert, A., Herrmann, B. and Robertson, E. J (1994). A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development 120, 1919-1928.[Abstract]

Cunliffe, V. and Smith, J. C (1992). Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature 358, 427-430.[Medline]

Dale, L. and Slack, J. M. W (1987). Fate map for the 32-cell stage of Xenopus laevis. Development 99, 527-551.[Abstract/Free Full Text]

De Chiara, T. M., Robertson, E. J. and Efstratiadis, A (1991). Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64, 849-859.[Medline]

Dush, M. K. and Martin, G. R (1992). Analysis of mouse Evx genes: Evx-1 displays graded expression in the primitive streak. Dev. Biol 151, 273-287.[Medline]

Echelard, Y., Epstein, D. J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A. and McMahon, A. P (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]

Faust, C. and Magnuson, T (1993). Genetic control of gastrulation in the mouse. Curr. Opin. Genet. Dev 3, 491-498.[Medline]

Gaunt, S. J., Blum, M. and De Robertis, E. M (1993). Expression of the mouse goosecoid gene during mid-embryogenesis may mark mesenchymal cell lineages in the developing head, limbs, and body wall. Development 117, 769-778.[Abstract]

Ginsburg, M., Snow, M. H. L. and McLaren, A (1990). Pimordial germ cells in the mouse embryo during gastrulation. Development 110, 521-528.[Abstract/Free Full Text]

Hebert, J. M., Boyle, M. and Martin, G. R (1991). mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation. Development 112, 407-415.[Abstract]

Herrmann, B. G. and Kispert, A (1994). The T genes in embryogenesis. Trends Genet 8, 281-286.

Herrmann, B. G., Labeit, S., Poustka, A., King, T. R. and Lehrach, H (1990). Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622.[Medline]

Iannaccone, P. M., Zhou, X., Khokha, M., Boucher, D. and Kuehn, M. R (1992). Insertional mutation of a gene involved in growth regulation of the early mouse embryo. Dev. Dynamics 194, 198-208.[Medline]

Izpisua-Belmonte, J. C., De Robertis, E. M., Storey, K. G. and Stern, C. D (1993). The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm. Cell 74, 645-659.[Medline]

Kimelman, D., Christian, J. L. and Moon, R. T (1992). Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction. Development 116, 1-9.[Abstract]

Kispert, A. and Herrmann, B. G (1994). Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev. Biol 161, 179-193.[Medline]

Lawson, K. A., Meneses, J. J. and Pedersen, R. A (1991). Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 113, 891-911.[Abstract]

Lawson, K. A. and Pedersen, R. A (1987). Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse. Development 101, 627-652.[Abstract]

Lee, J. E., Pintar, J. and Efstratiadis, A (1990). Pattern of insulin-like growth factor II gene expression during early mouse embryogenesis. Development 110, 151-159.[Abstract]

Mac Auley, A., Werb, Z. and Mirkes, P. E (1993). Characterization of the unusually rapid cell cycles during rat gastrulation. Development 117, 873-883.[Abstract]

McGadey, J (1970). A tetrazolium method for non-specific alkaline phosphatase. Histochemie 23, 180-184.[Medline]

Mansukhani, A., Moscatelli, D., Talarico, D., Levytska, V. and Basilico, C (1990). A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF. Proc. Natl. Acad. Sci. USA 87, 4378-4382.[Abstract/Free Full Text]

Monaghan, A. P., Kaestner, K. H., Grau, E. and Schutz, G (1993). Postimplantation expression patterns indicate a role for the mouse forkhead/ HNF3, , andgenes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development 119, 567-578.[Abstract]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Niswander, L., Yee, D., Rinchik, E. M., Russell, L. B. and Magnuson, T (1988). The albino deletion complex and early postimplantation survival in the mouse. Development 102, 45-53.[Abstract/Free Full Text]

Orr-Urtreger, A., Givol, D., Yayon, A., Yarden, Y. and Lonai, P (1991). Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113, 1419-1434.[Abstract]

Poelmann, R. E (1981). The formation of the embryonic mesoderm in the early post-implantation mouse embryo. Anat. Embryol 162, 29-40.[Medline]

Poelmann, R. E (1981). The head-process and the formation of the definitive endoderm in the mouse embryo. Anat. Embryol 162, 41-49.[Medline]

Popp, R. A., Bailiff, E. G., Skow, L. C., Johnson, F. M. and Lewis, S. E (1983). Analysis of a mouse-globin gene mutation induced by ethylnitrosourea. Genetics 105, 157-167.[Abstract/Free Full Text]

Provost, G. S. and Short, J. M (1994). Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice. Proc. Natl. Acad. Sci. USA 91, 6564-6568.[Abstract/Free Full Text]

Rashbass, P., Cooke, L. A., Herrmann, B. G. and Beddington, R. S. P (1991). A cell autonomous function of Brachyury in T / T embryonic stem cell chimeras. Nature 353, 348-351.[Medline]

Rinchik, E. M (1991). Chemical mutagenesis and fine-structure functional analysis of the mouse genome. Trends Genet 7, 15-21.[Medline]

Rinchik, E. M. and Carpenter, D. A (1993). N- ethyl- N -nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development ( eed ) locus on mouse Chromosome 7. Mammalian Genome 4, 349-353.[Medline]

Ruiz i Altaba, A., Choi, T. and Melton, D. A (1991). Expression of the Xhox3 homeobox protein in Xenopus embryos: blocking its early function suggests the requirement of Xhox3 for normal posterior development. Dev. Growth Dif 33, 651-669.

Ruiz i Altaba, A. and Melton, D. A (1989). Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development. Development 106, 173-183.[Abstract]

Ruiz i Altaba, A. and Melton, D. A (1989). Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis. Cell 57, 317-326.[Medline]

Ruiz i Altaba, A., Prezioso, V. R., Darnell, J. E. and Jessell, T. M (1993). Sequential expression of HNF-3 and HNF-3 by embryonic organizing centres: the doral lip/node, notochord and floor plate. Mech. Dev 44, 91-108.[Medline]

Russell, L. B., Montgomery, C. S. and Raymer, G. D (1982). Analysis of the albino-locus region of the mouse. IV. Characterization of 34 deficiencies. Genetics 100, 427-453.[Abstract/Free Full Text]

Sasaki, H. and Hogan, B. L. M (1993). Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118, 47-59.[Abstract]

Schulte-Merker, S., Hammerschmidt, M., Beuchle, D., Cho, K. W., De Robertis, E. M. and Nusslein-Volhard, C (1994). Expression of zebrafish goosecoid and notail gene products in wild-type and mutant no tail embryos. Development 120, 843-852.[Abstract]

Selleck, M. A. J. and Stern, C. D (1991). Fate mapping and cell lineage analysis of Hensen's node in the chick embryo. Development 112, 615-626.[Abstract]

Slack, J. M. W. and Tannahill, D (1992). Mechanism of anteroposterior axis specification in vertebrates: lessons from the amphibians. Development 114, 285-302.[Abstract]

Snow, M. H. L (1977). Gastrulation in the mouse: Growth and regionalization of the epiblast. J. Embryol. exp. Morph 42, 293-303.

Spyropoulos, D. and Capecchi, M. R (1994). Targeted disruption of the even-skipped gene, evx1 , causes early postimplantation lethality of the mouse conceptus. Genes Dev 8, 1949-1961.[Abstract/Free Full Text]

Stachel, S. E., Grunwald, D. J. and Meyers, P. Z (1993). LithiumC. Faust and others285Mesoderm production in miceperturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish. Development 117, 1261-1274.[Abstract]

Tam, P. P. L (1989). Regionalisation of the mouse embryonic ectoderm: allocation of prospective ectodermal tissues during gastrulation. Development 107, 55-67.[Abstract]

Weinstein, D. C., Ruiz i Altaba, A., Chen, W. S., Hoodless, P., Prezioso, V. R., Jessell, T. M. and Darnell Jr., J. E (1994). The winged-helix transcription factor HNF-3 is required for notochord development in the mouse embryo. Cell 78, 575-588.[Medline]

Wilkinson, D. G., Bhatt, S. and Herrmann, B. G (1990). Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 343, 657-659.[Medline]

Yamaguchi, T., Dumont, D. J., Conlon, R. A., Breitman, M. L. and Rossant, J (1993). flk-1 , an flt -related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development 118, 489-498.[Abstract]

Yamaguchi, T. P., Conlon, R. A. and Rossant, J (1992). Expression of the fibroblast growth factor FGFR-1/ flg during gastrulation and segmentation in the mouse. Dev. Biol 152, 75-88.[Medline]

Zhou, X., Sasaki, H., Lowe, L., Hogan, B. L. M. and Kuehn, M. R (1993). Nodal is a novel TGF--like gene expressed in the mouse node during gastrulation. Nature 361, 543-546.[Medline]

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				D. Pasini, K. H. Hansen, J. Christensen, K. Agger, P. A.C. Cloos, and K. Helin Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2 Genes & Dev., May 15, 2008; 22(10): 1345 - 1355. [Abstract] [Full Text] [PDF]

				M. Sauvageau, M. Miller, S. Lemieux, J. Lessard, J. Hebert, and G. Sauvageau Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia Blood, January 15, 2008; 111(2): 790 - 799. [Abstract] [Full Text] [PDF]

				V. K. Rajasekhar and M. Begemann Concise Review: Roles of Polycomb Group Proteins in Development and Disease: A Stem Cell Perspective Stem Cells, October 1, 2007; 25(10): 2498 - 2510. [Abstract] [Full Text] [PDF]

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				S. Y. Kim, J. M. Levenson, S. Korsmeyer, J. D. Sweatt, and A. Schumacher Developmental Regulation of Eed Complex Composition Governs a Switch in Global Histone Modification in Brain J. Biol. Chem., March 30, 2007; 282(13): 9962 - 9972. [Abstract] [Full Text] [PDF]

				Y. Yamasaki-Ishizaki, T. Kayashima, C. K. Mapendano, H. Soejima, T. Ohta, H. Masuzaki, A. Kinoshita, T. Urano, K.-i. Yoshiura, N. Matsumoto, et al. Role of DNA Methylation and Histone H3 Lysine 27 Methylation in Tissue-Specific Imprinting of Mouse Grb10 Mol. Cell. Biol., January 15, 2007; 27(2): 732 - 742. [Abstract] [Full Text] [PDF]

				S. Y. Kim, S. W. Paylor, T. Magnuson, and A. Schumacher Juxtaposed Polycomb complexes co-regulate vertebral identity Development, December 15, 2006; 133(24): 4957 - 4968. [Abstract] [Full Text] [PDF]

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				N. El Kassar, P. J. Lucas, D. B. Klug, M. Zamisch, M. Merchant, C. V. Bare, B. Choudhury, S. O. Sharrow, E. Richie, C. L. Mackall, et al. A dose effect of IL-7 on thymocyte development Blood, September 1, 2004; 104(5): 1419 - 1427. [Abstract] [Full Text] [PDF]

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				J. Gilthorpe, M. Vandromme, T. Brend, A. Gutman, D. Summerbell, N. Totty, and P. W. J. Rigby Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY Development, March 10, 2003; 129(16): 3887 - 3899. [Abstract] [Full Text] [PDF]

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				D. O'Carroll, S. Erhardt, M. Pagani, S. C. Barton, M. A. Surani, and T. Jenuwein The Polycomb-Group Gene Ezh2 Is Required for Early Mouse Development Mol. Cell. Biol., July 1, 2001; 21(13): 4330 - 4336. [Abstract] [Full Text] [PDF]

				T Yoshimizu, M Obinata, and Y Matsui Stage-specific tissue and cell interactions play key roles in mouse germ cell specification Development, January 2, 2001; 128(4): 481 - 490. [Abstract] [PDF]

				C. A Johnson Chromatin modification and disease J. Med. Genet., December 1, 2000; 37(12): 905 - 915. [Full Text]

				S Kitajima, A Takagi, T Inoue, and Y Saga MesP1 and MesP2 are essential for the development of cardiac mesoderm Development, January 8, 2000; 127(15): 3215 - 3226. [Abstract] [PDF]

				J. Lessard, A. Schumacher, U. Thorsteinsdottir, M. van Lohuizen, T. Magnuson, and G. Sauvageau Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation Genes & Dev., October 15, 1999; 13(20): 2691 - 2703. [Abstract] [Full Text]

				X. Sun, E. N. Meyers, M. Lewandoski, and G. R. Martin Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo Genes & Dev., July 15, 1999; 13(14): 1834 - 1846. [Abstract] [Full Text]

				E. M. Rinchik and D. A. Carpenter N-Ethyl-N-Nitrosourea Mutagenesis of a 6- to 11-cM Subregion of the Fah�Hbb Interval of Mouse Chromosome 7: Completed Testing of 4557 Gametes and Deletion Mapping and Complementation Analysis of 31 Mutations Genetics, May 1, 1999; 152(1): 373 - 383. [Abstract] [Full Text]

				K. A. Lawson, N. R. Dunn, B. A.J. Roelen, L. M. Zeinstra, A. M. Davis, C. V.E. Wright, J. P.W.F.M. Korving, and B. L.M. Hogan Bmp4 is required for the generation of primordial germ cells in the mouse embryo Genes & Dev., February 15, 1999; 13(4): 424 - 436. [Abstract] [Full Text]

				W Shawlot, M Wakamiya, K. Kwan, A Kania, T. Jessell, and R. Behringer Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse Development, January 11, 1999; 126(22): 4925 - 4932. [Abstract] [PDF]

				C Faust, K. Lawson, N. Schork, B Thiel, and T Magnuson The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo Development, January 11, 1998; 125(22): 4495 - 4506. [Abstract] [PDF]

				S. Tang, P. Hoodless, Z Lu, M. Breitman, R. McInnes, J. Wrana, and M Buchwald The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development Development, January 5, 1998; 125(10): 1877 - 1887. [Abstract] [PDF]

				S P Oh and E Li The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes & Dev., July 15, 1997; 11(14): 1812 - 1826. [Abstract] [PDF]

				S C Farmer, C W Sun, G E Winnier, B L Hogan, and T M Townes The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. Genes & Dev., March 15, 1997; 11(6): 786 - 798. [Abstract] [PDF]

				J C Baker and R M Harland A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes & Dev., August 1, 1996; 10(15): 1880 - 1889. [Abstract] [PDF]

				D Acampora, S Mazan, Y Lallemand, V Avantaggiato, M Maury, A Simeone, and P Brulet Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation Development, January 10, 1995; 121(10): 3279 - 3290. [Abstract] [PDF]