Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo

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R. Y. Osamura, S. Tahara, R. Kurotani, N. Sanno, A. Matsuno, and A. Teramoto
Contributions of Immunohistochemistry and In Situ Hybridization to the Functional Analysis of Pituitary Adenomas
J. Histochem. Cytochem., April 1, 2000; 48(4): 445 - 458.
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J. Huelsken, R. Vogel, V. Brinkmann, B. Erdmann, C. Birchmeier, and W. Birchmeier
Requirement for {beta}-Catenin in Anterior-Posterior Axis Formation in Mice
J. Cell Biol., February 7, 2000; 148(3): 567 - 578.
[Abstract] [Full Text] [PDF]

A. Foley, I Skromne, and C. Stern
Reconciling different models of forebrain induction and patterning: a dual role for the hypoblast
Development, January 9, 2000; 127(17): 3839 - 3854.
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J. Martinez Barbera, M Clements, P Thomas, T Rodriguez, D Meloy, D Kioussis, and R. Beddington
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation
Development, January 6, 2000; 127(11): 2433 - 2445.
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C. J. Phelps and D. L. Hurley
Pituitary Hormones as Neurotrophic Signals: Update on Hypothalamic Differentiation in Genetic Models of Altered Feedback
Experimental Biology and Medicine, October 2, 1999; 222(1): 39 - 58.
[Abstract] [Full Text]

X. Sun, E. N. Meyers, M. Lewandoski, and G. R. Martin
Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
Genes & Dev., July 15, 1999; 13(14): 1834 - 1846.
[Abstract] [Full Text]

C. Lanctôt, Y. Gauthier, and J. Drouin
Pituitary Homeobox 1 (Ptx1) Is Differentially Expressed during Pituitary Development
Endocrinology, March 1, 1999; 140(3): 1416 - 1422.
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W Shawlot, M Wakamiya, K. Kwan, A Kania, T. Jessell, and R. Behringer
Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse
Development, January 11, 1999; 126(22): 4925 - 4932.
[Abstract] [PDF]

J. Zoltewicz, N. Plummer, M. Lin, and A. Peterson
oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1
Development, January 11, 1999; 126(22): 5085 - 5095.
[Abstract] [PDF]

P. Tam and K. Steiner
Anterior patterning by synergistic activity of the early gastrula organizer and the anterior germ layer tissues of the mouse embryo
Development, January 11, 1999; 126(22): 5171 - 5179.
[Abstract] [PDF]

M Rhinn, A Dierich, M Le Meur, and S Ang
Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain
Development, January 10, 1999; 126(19): 4295 - 4304.
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G. Ermakova, E. Alexandrova, O. Kazanskaya, O. Vasiliev, M. Smith, and A. Zaraisky
The homeobox gene, Xanf-1, can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo
Development, January 10, 1999; 126(20): 4513 - 4523.
[Abstract] [PDF]

P. Gage, H Suh, and S. Camper
Dosage requirement of Pitx2 for development of multiple organs
Development, January 10, 1999; 126(20): 4643 - 4651.
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T Theil, G Alvarez-Bolado, A Walter, and U Ruther
Gli3 is required for Emx gene expression during dorsal telencephalon development
Development, January 8, 1999; 126(16): 3561 - 3571.
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Y Suda, J Nakabayashi, I Matsuo, and S Aizawa
Functional equivalency between Otx2 and Otx1 in development of the rostral head
Development, January 2, 1999; 126(4): 743 - 757.
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H Knoetgen, C Viebahn, and M Kessel
Head induction in the chick by primitive endoderm of mammalian, but not avian origin
Development, January 2, 1999; 126(4): 815 - 825.
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S. L. Asa and S. Ezzat
The Cytogenesis and Pathogenesis of Pituitary Adenomas
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				C. L. Andoniadou, M. Signore, E. Sajedi, C. Gaston-Massuet, D. Kelberman, A. J. Burns, N. Itasaki, M. Dattani, and J. P. Martinez-Barbera Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain Development, April 15, 2007; 134(8): 1499 - 1508. [Abstract] [Full Text] [PDF]

				M.-L. Sobrier, M. Maghnie, M.-P. Vie-Luton, A. Secco, N. di Iorgi, R. Lorini, and S. Amselem Novel HESX1 Mutations Associated with a Life-Threatening Neonatal Phenotype, Pituitary Aplasia, but Normally Located Posterior Pituitary and No Optic Nerve Abnormalities J. Clin. Endocrinol. Metab., November 1, 2006; 91(11): 4528 - 4536. [Abstract] [Full Text] [PDF]

				V. Ribes, Z. Wang, P. Dolle, and K. Niederreither Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling Development, January 15, 2006; 133(2): 351 - 361. [Abstract] [Full Text] [PDF]

				E. M. Morin-Kensicki, B. N. Boone, M. Howell, J. R. Stonebraker, J. Teed, J. G. Alb, T. R. Magnuson, W. O'Neal, and S. L. Milgram Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65 Mol. Cell. Biol., January 1, 2006; 26(1): 77 - 87. [Abstract] [Full Text] [PDF]

				D. Stickens, B. M. Zak, N. Rougier, J. D. Esko, and Z. Werb Mice deficient in Ext2 lack heparan sulfate and develop exostoses Development, November 15, 2005; 132(22): 5055 - 5068. [Abstract] [Full Text] [PDF]

				N. Gotoh, K. Manova, S. Tanaka, M. Murohashi, Y. Hadari, A. Lee, Y. Hamada, T. Hiroe, M. Ito, T. Kurihara, et al. The Docking Protein FRS2{alpha} Is an Essential Component of Multiple Fibroblast Growth Factor Responses during Early Mouse Development Mol. Cell. Biol., May 15, 2005; 25(10): 4105 - 4116. [Abstract] [Full Text] [PDF]

				X. Zhao, R. Teng, K. Asanuma, Y. Okouchi, K. Johkura, N. Ogiwara, and K. Sasaki Differentiation of Mouse Embryonic Stem Cells Into Gonadotrope-like Cells In Vitro Reproductive Sciences, May 1, 2005; 12(4): 257 - 262. [Abstract] [PDF]

				P. E Mullis Genetic control of growth Eur. J. Endocrinol., January 1, 2005; 152(1): 11 - 31. [Abstract] [Full Text] [PDF]

				O. G. Kelly, K. I. Pinson, and W. C. Skarnes The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice Development, June 15, 2004; 131(12): 2803 - 2815. [Abstract] [Full Text] [PDF]

				N. Martynova, F. Eroshkin, G. Ermakova, A. Bayramov, J. Gray, R. Grainger, and A. Zaraisky Patterning the forebrain: FoxA4a/Pintallavis and Xvent2 determine the posterior limit of Xanf1 expression in the neural plate Development, May 15, 2004; 131(10): 2329 - 2338. [Abstract] [Full Text] [PDF]

				A. Voutetakis, M. Argyropoulou, A. Sertedaki, S. Livadas, P. Xekouki, M. Maniati-Christidi, I. Bossis, N. Thalassinos, N. Patronas, and C. Dacou-Voutetakis Pituitary Magnetic Resonance Imaging in 15 Patients with Prop1 Gene Mutations: Pituitary Enlargement May Originate from the Intermediate Lobe J. Clin. Endocrinol. Metab., May 1, 2004; 89(5): 2200 - 2206. [Abstract] [Full Text] [PDF]

				S. Srinivas, T. Rodriguez, M. Clements, J. C. Smith, and R. S. P. Beddington Active cell migration drives the unilateral movements of the anterior visceral endoderm Development, March 1, 2004; 131(5): 1157 - 1164. [Abstract] [Full Text] [PDF]

				S. C. Chapman, F. R. Schubert, G. C. Schoenwolf, and A. Lumsden Anterior identity is established in chick epiblast by hypoblast and anterior definitive endoderm Development, November 1, 2003; 130(21): 5091 - 5101. [Abstract] [Full Text] [PDF]

				R. N. Cohen, L. E. Cohen, D. Botero, C. Yu, A. Sagar, M. Jurkiewicz, and S. Radovick Enhanced Repression by HESX1 as a Cause of Hypopituitarism and Septooptic Dysplasia J. Clin. Endocrinol. Metab., October 1, 2003; 88(10): 4832 - 4839. [Abstract] [Full Text] [PDF]

				I. del Barco Barrantes, G. Davidson, H.-J. Grone, H. Westphal, and C. Niehrs Dkk1 and noggin cooperate in mammalian head induction Genes & Dev., September 15, 2003; 17(18): 2239 - 2244. [Abstract] [Full Text] [PDF]

				H. Suh, P. J. Gage, J. Drouin, and S. A. Camper Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification Development, March 3, 2003; 129(2): 329 - 337. [Abstract] [Full Text] [PDF]

				T. Tajima, T. Hattorri, T. Nakajima, K. Okuhara, K. Sato, S. Abe, J. Nakae, and K. Fujieda Sporadic Heterozygous Frameshift Mutation of HESX1 Causing Pituitary and Optic Nerve Hypoplasia and Combined Pituitary Hormone Deficiency in a Japanese Patient J. Clin. Endocrinol. Metab., January 1, 2003; 88(1): 45 - 50. [Abstract] [Full Text] [PDF]

				L. E. Olson, J. S. Dasen, B. Gun Ju, J. Tollkuhn, and M. G. Rosenfeld Paired-like Repression/Activation in Pituitary Development Recent Prog. Horm. Res., January 1, 2003; 58(1): 249 - 261. [Abstract] [Full Text] [PDF]

				L. E. Cohen and S. Radovick Molecular Basis of Combined Pituitary Hormone Deficiencies Endocr. Rev., August 1, 2002; 23(4): 431 - 442. [Abstract] [Full Text] [PDF]

				M.-H. Quentien, F. Pitoia, G. Gunz, M.-P. Guillet, A. Enjalbert, and I. Pellegrini Regulation of Prolactin, GH, and Pit-1 Gene Expression in Anterior Pituitary by Pitx2: An Approach Using Pitx2 Mutants Endocrinology, August 1, 2002; 143(8): 2839 - 2851. [Abstract] [Full Text] [PDF]

				L. E. Olson and M. G. Rosenfeld Perspective: Genetic and Genomic Approaches in Elucidating Mechanisms of Pituitary Development Endocrinology, June 1, 2002; 143(6): 2007 - 2011. [Abstract] [Full Text] [PDF]

				K. M. Scully and M. G. Rosenfeld Pituitary Development: Regulatory Codes in Mammalian Organogenesis Science, March 22, 2002; 295(5563): 2231 - 2235. [Abstract] [Full Text] [PDF]

				J. M. Brickman, M. Clements, R. Tyrell, D. McNay, K. Woods, J. Warner, A. Stewart, R. S. P. Beddington, and M. Dattani Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders Development, December 15, 2001; 128(24): 5189 - 5199. [Abstract] [Full Text] [PDF]

				J. S. Dasen, J.-P. M. Barbera, T. S. Herman, S. O' Connell, L. Olson, B. Ju, J. Tollkuhn, S. H. Baek, D. W. Rose, and M. G. Rosenfeld Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis Genes & Dev., December 1, 2001; 15(23): 3193 - 3207. [Abstract] [Full Text] [PDF]

				F. G. Riepe, C.-J. Partsch, O. Blankenstein, H. Monig, R. W. Pfaffle, and W. G. Sippell Longitudinal Imaging Reveals Pituitary Enlargement Preceding Hypoplasia in Two Brothers with Combined Pituitary Hormone Deficiency Attributable to PROP1 Mutation J. Clin. Endocrinol. Metab., September 1, 2001; 86(9): 4353 - 4357. [Abstract] [Full Text] [PDF]

				P. A. Hoodless, M. Pye, C. Chazaud, E. Labbé, L. Attisano, J. Rossant, and J. L. Wrana FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse Genes & Dev., May 15, 2001; 15(10): 1257 - 1271. [Abstract] [Full Text]

				L. J. Cushman, D. E. Watkins-Chow, M. L. Brinkmeier, L. T. Raetzman, A. L. Radak, R. V. Lloyd, and S. A. Camper Persistent Prop1 expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility Hum. Mol. Genet., May 1, 2001; 10(11): 1141 - 1153. [Abstract] [Full Text] [PDF]

				B. Andersen and M. G. Rosenfeld POU Domain Factors in the Neuroendocrine System: Lessons from Developmental Biology Provide Insights into Human Disease Endocr. Rev., February 1, 2001; 22(1): 2 - 35. [Abstract] [Full Text]

				L. Lowe, S Yamada, and M. Kuehn Genetic dissection of nodal function in patterning the mouse embryo Development, January 5, 2001; 128(10): 1831 - 1843. [Abstract] [PDF]

				P. Q. Thomas, M. T. Dattani, J. M. Brickman, D. McNay, G. Warne, M. Zacharin, F. Cameron, J. Hurst, K. Woods, D. Dunger, et al. Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia Hum. Mol. Genet., January 1, 2001; 10(1): 39 - 45. [Abstract] [Full Text] [PDF]