Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos

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Blumberg, B., Wright, C. V. E., De Robertis, E. M. and Cho, K. W. Y (1991). Organizer-specific homeobox genes in Xenopus laevis embryos. Science 253, 194-196.[Abstract/Free Full Text]

Cho, K. W. Y. and De Robertis, E. M (1990). Differential activation of Xenopus homeobox genes by mesoderm-inducing growth factors and retinoic acid. Genes Dev 4, 1910-1916.[Abstract/Free Full Text]

Cho, K. W. Y., Blumberg, B, Steinbeisser, H. and De Robertis, E. M (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.[Medline]

Christian, J. L. and Moon, R. T (1993). Interactions between Xwnt-8 and Spemann organizer signalling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev 7, 13-28.[Abstract/Free Full Text]

Condie, B. G., Hemmati-Brivanlou, A. H. and Harland, R. M (1990). Most of the homeobox-containing Xhox 36 transcripts in early Xenopus embryos cannot encode a homeodomain protein. Mol. Cell Biol 10, 3376-3385.[Abstract/Free Full Text]

Dale, L. and Slack, J. M. W (1987). Fate map for the 32-cell stage of Xenopus laevis. Development 99, 527-551.[Abstract/Free Full Text]

Dale, L. and Slack, J. M. W (1987). Regional specification within the mesoderm of early embryos of Xenopus laevis. Development 100, 279-295.[Abstract/Free Full Text]

Dale, L. Smith, J. C. and Slack, J. M. W (1985). Mesoderm induction in Xenopus laevis : a quantitative study using a cell lineage label and tissue specific antibodies. J. Embryol. Exp. Morph 89, 289-312.[Medline]

Dale, L., Howes, G., Price, B. M. J. and Smith, J. C (1992). Bone morphogenetic protein 4: A ventralising factor in early Xenopus development. Development 115, 573-585.[Abstract]

Fainsod, A., Steinbeisser, H. and De Robertis, E. M (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J 13, 5015-5025.[Medline]

Ferguson, E. L. and Anderson, K. V (1992). decapentaplegic acts as a morphogen to organise dorso-ventral pattern in the Drosophila embryo. Cell 71, 451-461.[Medline]

Fran\215ois, V. and Bier, E (1995). Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation. Cell 80, 19-20.[Medline]

Fran\215ois, V. Solloway, M., O'Neill, J. W., Emery, J. and Bier, E (1994). Dorso-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes Dev 8, 2602-2616.[Abstract/Free Full Text]

Gimlich, R. L. and Gerhart, J. C (1984). Early cellular interactions promote embryonic axis formation in Xenopus laevis. Dev. Biol 104, 117-130.[Medline]

Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.[Medline]

Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A (1994). Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.[Medline]

Hemmati-Brivanlou, A. and Thomsen, G. H (1995). Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP-2 and BMP-4. Dev. Genet 17, 78-89.[Medline]

Holley, S. A., Jackson, P. D., Sasai, Y., Lu, B., De Robertis, E. M., Hoffman, F. M. and Ferguson, E. L (1995). A conserved system for dorso-ventral patterning in insects and vertebrates involving sog and chordin. Nature 376, 249-253.[Medline]

Hogan, B. L. M., Blessing, M., Winnier, M. B., Suzuki, N. and Jones, C. M (1994). Growth factors in development: the role of TGF-\247 related polypeptide signalling molecules in embryogenesis. Development 1994, 53-60.

Ishikawa, T., Yoshioka, H., Ohuchi, H., Noji, S. and Noho, T (1995). Truncated type II receptor for BMP-4 induces secondary axial structures in Xenopus embryos. Biochem. Biophys. Res. Comm 216, 26-33.[Medline]

Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. E. and Hogan, B. L. M (1992). DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.[Abstract]

Jones, C. M. and Smith, J. C (1995). Revolving vertebrates. Current Biol 5, 574-576.[Medline]

Jones, C. M., Kuehn, M. R., Hogan, B. L. M., Smith, J. C. and Wright, C. V. E (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-3662.[Abstract]

Kao, K. R. and Elinson, R. P (1988). The entire mesodermal mantle behaves as Spemann's organizer in dorso-anterior enhanced Xenopus laevis embryos. Dev. Biol 127, 64-77.[Medline]

Kessler, D. S. and Melton, D. A (1995). Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121, 2155-2164.[Abstract]

Kintner, C. R. and Brockes, J. P (1984). Monoclonal antibodies identify blastema cells derived from differentiating muscle in newt limb regeneration. Nature 308, 67-69.[Medline]

K\232ster, M., Plessow, S., Clement, J. H., Lorenz, A., Tiedemann, H. and Kn\232chel, W (1991). Bone morphogenetic protein 4 (BMP-4) a member of the TGF-family in early embryos of Xenopus laevis : analysis of mesoderm inducing activity. Mech. Dev 33, 191-200.[Medline]

Krieg, P. A., Varnum, S. M., Wormington, W. M. and Melton, D. A (1989). The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus. Dev. Biol 133, 93-100.[Medline]

Lettice, L. A. and Slack, J. M. W (1993). Properties of the dorsalizing signal in gastrulae of Xenopus laevis. Development 117, 263-271.[Abstract]

Maeno, M., Ong, R. C., Suzuki, A., Ueno, N., Kung, H. F (1994). A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm. Proc. Natl. Acad. Sci. USA 91, 10260-10264.[Abstract/Free Full Text]

Mohun, T. J., Brennan, S., Dathan, N., Fairman, S. and Gurdon, J. B (1984). Cell type specific activation of actin genes in the early amphibian embryo. Nature 311, 715-721.

Moody, S. A (1987). Fates of the blastomeres of the 32 cell Xenopus embryo. Dev. Biol 122, 300-319.[Medline]

Nishimatsu, S., Suzuki, A., Shoda, A., Murakami, K. and Ueno, N (1992). Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos. Biochem. Biophys. Res. Comm 186, 1487-1495.[Medline]

O'Reilly, M.-A. J., Smith, J. C. and Cunliffe, V (1995). Patterning of the mesoderm in Xenopus : dose-dependent and synergistic effects of Brachyury and Pintallavis. Development 121, 1351-1359.[Abstract]

Re'em-Kalma, Y., Lamb, T. and Frank, D (1995). Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development. Proc. Natn. Acad. Sci. USA 92, 12141-12145.[Abstract/Free Full Text]

Ruiz i Altaba, A. and Jessell, T. M (1992). Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis. Development 116, 81-93.[Abstract]

Ruiz i Altaba, A. and Melton, D (1989). Bimodal and graded expression of the Xenopus homeobox gene Xhox3. Development 106, 173-183.[Abstract]

Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M (1994). Xenopus chordin : A novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.[Medline]

Sasai, Y., Lu, B., Steinbeisser, H. and De Robertis, E. M (1995). Regulation of neural induction by the Chd and BMP-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.[Medline]

Sargent, M. G. and Bennett, M. F (1990). Identification in Xenopus of a structural homologue of the Drosophila gene snail. Development 109, 967-973.[Abstract/Free Full Text]

Schmidt, J. E., Suzuki, A., Ueno, N. and Kimelman, D (1995). Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Development 169, 37-50.

Sive, H (1993). The frog prince-ss: A molecular formula for dorsoventral patterning in Xenopus. Genes Dev 7, 1-12.[Free Full Text]

Slack, J. M. W (1984). Regional biosynthetic markers in the early amphibian embryo. J. Embryo. Exp. Morph 80, 289-319.[Medline]

Slack, J. M. W. and Forman, D (1980). An interaction between dorsal and ventral regions of the marginal zone in early amphibian embryos. J. Embryol. Exp. Morph 56, 283-299.[Medline]

Slack, J. M. W. and Isaacs, H. V (1994). The Einsteck-method: position and structure of projections formed by implants of a ventral character. Dev. Biol 161, 313-317.[Medline]

Smith, J. C., Price, B. M. J., Van Nimmen, K. and Huylebroeck, D (1990). Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A. Nature 345, 729-731.[Medline]

Smith, J. C. and Slack, J. M. W (1983). Dorsalization and neural induction: properties of the organizer in Xenopus laevis. J. Embryol. Exp. Morph 78, 299-317.[Medline]

Smith, J.C. and Watt, F.M (1985). Biochemical specificity of Xenopus notochord. Differentiation 29, 109-115.[Medline]

Smith, W. C. and Harland, R. M (1992). Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-840.[Medline]

Smith, W. C., McKendry, R. M., Ribisi, S. and Harland, R. M (1995). A nodal -related gene defines a physical and functional domain within the Spemann Organizer. Cell 82, 37-46.[Medline]

Smith, W. C., Knecht, A. K., Wu, M. and Harland, R. M (1993). Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature 361, 547-549.[Medline]

Suzuki, A., Theis, R. S., Yamaji, N., Song, J. J., Wozney, J. M., Murakami, K. and Ueno, N (1994). A truncated BMP receptor affects dorso-ventral patterning in the early Xenopus embryo. Proc. Natl. Acad. Sci. USA 91, 10255-10259.[Abstract/Free Full Text]

Suzuki, A., Shioda, N. and Ueno, N (1995). Bone morphogenetic protein acts as a ventral mesoderm modifier in early Xenopus embryos. Develop. Growth Differ 37, 581-588.

Thomsen, G., Woolf, T., Whitman, M., Sokel, S., Vaughan, J., Vale, W. and Melton, D. A (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-493.[Medline]

Thomsen, G. and Melton, D. A (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-441.[Medline]

von Dassow, G., Schmidt, J. E. and Kimelman, D (1993). Induction of the Xenopus organizer: expression and regulation of Xnot , a novel FGF and activin-regulated homeobox gene. Genes Dev 7, 355-366.[Abstract/Free Full Text]

Wilson, P. A. and Hemmati-Brivanlou, A (1995). Induction of epidermis and inhibition of neural fate by BMP-4. Nature 376, 331-333.[Medline]

Xu, R-H., Kim, J., Taira, M., Zhan, S, Sredni, D and Kung, H-F (1995). A dominant negative bone morphogenetic protein 4 receptor causes neuralization in Xenopus ectoderm. Biochem. Biophys. Res. Comm 212, 212-219.[Medline]

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				K.-W. Cho, J.-Y. Kim, S.-J. Song, E. Farrell, M. C. Eblaghie, H.-J. Kim, C. Tickle, and H.-S. Jung Molecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland development PNAS, November 7, 2006; 103(45): 16788 - 16793. [Abstract] [Full Text] [PDF]

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				M. Schmerer and T. Evans Primitive erythropoiesis is regulated by Smad-dependent signaling in postgastrulation mesoderm Blood, November 1, 2003; 102(9): 3196 - 3205. [Abstract] [Full Text] [PDF]

				I. L. Blitz, K. W. Y. Cho, and C. Chang Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis Development, October 15, 2003; 130(20): 4975 - 4988. [Abstract] [Full Text] [PDF]

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				Y. Miyanaga, I. Torregroza, and T. Evans A Maternal Smad Protein Regulates Early Embryonic Apoptosis in Xenopus laevis Mol. Cell. Biol., March 1, 2002; 22(5): 1317 - 1328. [Abstract] [Full Text] [PDF]

				V. A. Schneider and M. Mercola Wnt antagonism initiates cardiogenesis in Xenopus laevis Genes & Dev., February 1, 2001; 15(3): 304 - 315. [Abstract] [Full Text]

				H Weber, C. Symes, M. Walmsley, A. Rodaway, and R. Patient A role for GATA5 in Xenopus endoderm specification Development, January 10, 2000; 127(20): 4345 - 4360. [Abstract] [PDF]

				S Faure, M. Lee, T Keller, P ten Dijke, and M Whitman Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development Development, January 7, 2000; 127(13): 2917 - 2931. [Abstract] [PDF]

				J. Brickman, C. Jones, M Clements, J. Smith, and R. Beddington Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function Development, January 6, 2000; 127(11): 2303 - 2315. [Abstract] [PDF]

				L. Angerer, D. Oleksyn, C. Logan, D. McClay, L Dale, and R. Angerer A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis Development, January 3, 2000; 127(5): 1105 - 1114. [Abstract] [PDF]

				N. A. Armes, K. A. Neal, and J. C. Smith A Short Loop on the ALK-2 and ALK-4 Activin Receptors Regulates Signaling Specificity but Cannot Account for All Their Effects on Early Xenopus Development J. Biol. Chem., March 19, 1999; 274(12): 7929 - 7935. [Abstract] [Full Text] [PDF]

				M Hild, A Dick, G. Rauch, A Meier, T Bouwmeester, P Haffter, and M Hammerschmidt The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo Development, January 5, 1999; 126(10): 2149 - 2159. [Abstract] [PDF]

				L Pardanaud and F Dieterlen-Lievre Manipulation of the angiopoietic/hemangiopoietic commitment in the avian embryo Development, January 2, 1999; 126(4): 617 - 627. [Abstract] [PDF]

				T. L. Huber, Y. Zhou, P. E. Mead, and L. I. Zon Cooperative Effects of Growth Factors Involved in the Induction of Hematopoietic Mesoderm Blood, December 1, 1998; 92(11): 4128 - 4137. [Abstract] [Full Text] [PDF]

				T. Sykes, A. Rodaway, M. Walmsley, and R. Patient Suppression of GATA factor activity causes axis duplication in Xenopus Development, January 12, 1998; 125(23): 4595 - 4605. [Abstract] [PDF]

				A Frisch and C. Wright XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues Development, January 2, 1998; 125(3): 431 - 442. [Abstract] [PDF]

				A Streit, K. Lee, I Woo, C Roberts, T. Jessell, and C. Stern Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo Development, January 2, 1998; 125(3): 507 - 519. [Abstract] [PDF]

				A. Candia, T Watabe, S. Hawley, D Onichtchouk, Y Zhang, R Derynck, C Niehrs, and K. Cho Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads Development, January 11, 1997; 124(22): 4467 - 4480. [Abstract] [PDF]

				N. Armes and J. Smith The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds Development, January 10, 1997; 124(19): 3797 - 3804. [Abstract] [PDF]

				R Dosch, V Gawantka, H Delius, C Blumenstock, and C Niehrs Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus Development, January 6, 1997; 124(12): 2325 - 2334. [Abstract] [PDF]

				C. Hansen, C. Marion, K Steele, S George, and W. Smith Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3 Development, January 1, 1997; 124(2): 483 - 492. [Abstract] [PDF]

				M Hammerschmidt, G N Serbedzija, and A P McMahon Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes & Dev., October 1, 1996; 10(19): 2452 - 2461. [Abstract] [PDF]

				B L Hogan Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes & Dev., July 1, 1996; 10(13): 1580 - 1594. [PDF]

				R Ladher, T. Mohun, J. Smith, and A. Snape Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4 Development, January 8, 1996; 122(8): 2385 - 2394. [Abstract] [PDF]