Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb

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M. Logan and C. J. Tabin
Role of Pitx1 Upstream of Tbx4 in Specification of Hindlimb Identity
Science, March 12, 1999; 283(5408): 1736 - 1739.
[Abstract] [Full Text]

J. Gemel, C. Jacobsen, and C. A. MacArthur
Fibroblast Growth Factor-8 Expression Is Regulated by Intronic Engrailed and Pbx1-binding Sites
J. Biol. Chem., February 26, 1999; 274(9): 6020 - 6026.
[Abstract] [Full Text] [PDF]

L Lettice, J Hecksher-Sorensen, and R. Hill
The dominant hemimelia mutation uncouples epithelial-mesenchymal interactions and disrupts anterior mesenchyme formation in mouse hindlimbs
Development, January 11, 1999; 126(21): 4729 - 4736.
[Abstract] [PDF]

G Minowada, L. Jarvis, C. Chi, A Neubuser, X Sun, N Hacohen, M. Krasnow, and G. Martin
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
Development, January 10, 1999; 126(20): 4465 - 4475.
[Abstract] [PDF]

H Shamim, R Mahmood, C Logan, P Doherty, A Lumsden, and I Mason
Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
Development, January 2, 1999; 126(5): 945 - 959.
[Abstract] [PDF]

I Munoz-Sanjuan, B. Simandl, J. Fallon, and J Nathans
Expression of chicken fibroblast growth factor homologous factor (FHF)-1 and of differentially spliced isoforms of FHF-2 during development and involvement of FHF-2 in chicken limb development
Development, January 1, 1999; 126(2): 409 - 421.
[Abstract] [PDF]

H. Min, D. M. Danilenko, S. A. Scully, B. Bolon, B. D. Ring, J. E. Tarpley, M. DeRose, and W. S. Simonet
Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless
Genes & Dev., October 15, 1998; 12(20): 3156 - 3161.
[Abstract] [Full Text]

G. R. Martin
The roles of FGFs in the early development of vertebrate�limbs
Genes & Dev., June 1, 1998; 12(11): 1571 - 1586.
[Full Text]

M. Kengaku, J. Capdevila, C. Rodriguez-Esteban, J. De La Peña, R. L. Johnson, J. C. I. Belmonte, and C. J. Tabin
Distinct WNT Pathways Regulating AER Formation and Dorsoventral Polarity in the Chick Limb Bud
Science, May 22, 1998; 280(5367): 1274 - 1277.
[Abstract] [Full Text]

R. Jiang, Y. Lan, H. D. Chapman, C. Shawber, C. R. Norton, D. V. Serreze, G. Weinmaster, and T. Gridley
Defects in limb, craniofacial, and thymic development in Jagged2 mutant�mice
Genes & Dev., April 1, 1998; 12(7): 1046 - 1057.
[Abstract] [Full Text]

L. Sherman, D. Wainwright, H. Ponta, and P. Herrlich
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb�outgrowth
Genes & Dev., April 1, 1998; 12(7): 1058 - 1071.
[Abstract] [Full Text]

M Araujo, M. Piedra, M. Herrera, M. Ros, and M. Nieto
The expression and regulation of chick EphA7 suggests roles in limb patterning and innervation
Development, January 11, 1998; 125(21): 4195 - 4204.
[Abstract] [PDF]

M Takahashi, K Tamura, D Buscher, H Masuya, S Yonei-Tamura, K Matsumoto, M Naitoh-Matsuo, J Takeuchi, K Ogura, T Shiroishi, et al.
The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development
Development, January 11, 1998; 125(22): 4417 - 4425.
[Abstract] [PDF]

C Rodriguez-Esteban, J. Schwabe, J. Pena, D. Rincon-Limas, J Magallon, J Botas, and J. Belmonte
Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth
Development, January 10, 1998; 125(20): 3925 - 3934.
[Abstract] [PDF]

M Weinstein, X Xu, K Ohyama, and C. Deng
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
Development, January 9, 1998; 125(18): 3615 - 3623.
[Abstract] [PDF]

M Logan, H. Simon, and C Tabin
Differential regulation of T-box and homeobox transcription factors suggests roles in controlling chick limb-type identity
Development, January 8, 1998; 125(15): 2825 - 2835.
[Abstract] [PDF]

F Reifers, H Bohli, E. Walsh, P. Crossley, D. Stainier, and M Brand
Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
Development, January 7, 1998; 125(13): 2381 - 2395.
[Abstract] [PDF]

J. Gibson-Brown, S. Agulnik, L. Silver, L Niswander, and V. Papaioannou
Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development
Development, January 7, 1998; 125(13): 2499 - 2509.
[Abstract] [PDF]

				F. Muller, H. Rohrer, and A. Vogel-Hopker Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo Development, October 1, 2007; 134(19): 3483 - 3493. [Abstract] [Full Text] [PDF]

				T. Kobayashi, H. Habuchi, K. Tamura, H. Ide, and K. Kimata Essential Role of Heparan Sulfate 2-O-Sulfotransferase in Chick Limb Bud Patterning and Development J. Biol. Chem., July 6, 2007; 282(27): 19589 - 19597. [Abstract] [Full Text] [PDF]

				N. Mercader, S. Fischer, and C. J. Neumann Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction Development, August 1, 2006; 133(15): 2805 - 2815. [Abstract] [Full Text] [PDF]

				Y. Gibert, A. Gajewski, A. Meyer, and G. Begemann Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling Development, July 15, 2006; 133(14): 2649 - 2659. [Abstract] [Full Text] [PDF]

				J. G. M. Thewissen, M. J. Cohn, L. S. Stevens, S. Bajpai, J. Heyning, and W. E. Horton Jr. Developmental basis for hind-limb loss in dolphins and origin of the cetacean bodyplan PNAS, May 30, 2006; 103(22): 8414 - 8418. [Abstract] [Full Text] [PDF]

				J. A. Groves, C. L. Hammond, and S. M. Hughes Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish Development, October 1, 2005; 132(19): 4211 - 4222. [Abstract] [Full Text] [PDF]

				A. O. Perantoni, O. Timofeeva, F. Naillat, C. Richman, S. Pajni-Underwood, C. Wilson, S. Vainio, L. F. Dove, and M. Lewandoski Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development Development, September 1, 2005; 132(17): 3859 - 3871. [Abstract] [Full Text] [PDF]

				C. Rallis, J. Del Buono, and M. P. O. Logan Tbx3 can alter limb position along the rostrocaudal axis of the developing embryo Development, April 15, 2005; 132(8): 1961 - 1970. [Abstract] [Full Text] [PDF]

				Y. Kawakami, C. R. Esteban, T. Matsui, J. Rodriguez-Leon, S. Kato, and J. C. I. Belmonte Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos Development, October 1, 2004; 131(19): 4763 - 4774. [Abstract] [Full Text] [PDF]

				S. Fischer, B. W. Draper, and C. J. Neumann The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation Development, August 1, 2003; 130(15): 3515 - 3524. [Abstract] [Full Text] [PDF]

				J. K. Takeuchi, K. Koshiba-Takeuchi, T. Suzuki, M. Kamimura, K. Ogura, and T. Ogura Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade Development, June 15, 2003; 130(12): 2729 - 2739. [Abstract] [Full Text] [PDF]

				C. Rallis, B. G. Bruneau, J. Del Buono, C. E. Seidman, J. G. Seidman, S. Nissim, C. J. Tabin, and M. P. O. Logan Tbx5 is required for forelimb bud formation and continued outgrowth Development, June 15, 2003; 130(12): 2741 - 2751. [Abstract] [Full Text] [PDF]

				J. K. Ng, Y. Kawakami, D. Buscher, A. Raya, T. Itoh, C. M. Koth, C. R. Esteban, J. Rodriguez-Leon, D. M. Garrity, M. C. Fishman, et al. The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10 Development, March 13, 2003; 129(22): 5161 - 5170. [Abstract] [Full Text] [PDF]

				Y. Liu, C. Liu, Y. Yamada, and C.-M. Fan growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb Development, March 13, 2003; 129(22): 5289 - 5300. [Abstract] [Full Text] [PDF]

				P. Agarwal, J. N. Wylie, J. Galceran, O. Arkhitko, C. Li, C. Deng, R. Grosschedl, and B. G. Bruneau Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo Development, February 1, 2003; 130(3): 623 - 633. [Abstract] [Full Text] [PDF]

				S. C. Ahlgren, V. Thakur, and M. Bronner-Fraser Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure PNAS, August 6, 2002; 99(16): 10476 - 10481. [Abstract] [Full Text] [PDF]

				P. de Santa Barbara and D. J. Roberts Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13 Development, January 2, 2002; 129(3): 551 - 561. [Abstract] [Full Text] [PDF]

				K. Ahn, Y. Mishina, M. C. Hanks, R. R. Behringer, and E. B. Crenshaw III BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb Development, November 15, 2001; 128(22): 4449 - 4461. [Abstract] [Full Text] [PDF]

				R. Haraguchi, R. Mo, C.-c. Hui, J. Motoyama, S. Makino, T. Shiroishi, W. Gaffield, and G. Yamada Unique functions of Sonic hedgehog signaling during external genitalia development Development, November 1, 2001; 128(21): 4241 - 4250. [Abstract] [Full Text] [PDF]

				R. A. Kimmel, D. H. Turnbull, V. Blanquet, W. Wurst, C. A. Loomis, and A. L. Joyner Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation Genes & Dev., June 1, 2000; 14(11): 1377 - 1389. [Abstract] [Full Text]

				A. Tavares, T Tsukui, and J. Izpisua Belmonte Evidence that members of the Cut/Cux/CDP family may be involved in AER positioning and polarizing activity during chick limb development Development, January 12, 2000; 127(23): 5133 - 5144. [Abstract] [PDF]

				I Ruvinsky and J. Gibson-Brown Genetic and developmental bases of serial homology in vertebrate limb evolution Development, January 12, 2000; 127(24): 5233 - 5244. [Abstract] [PDF]

				N Bertrand, F Medevielle, and F Pituello FGF signalling controls the timing of Pax6 activation in the neural tube Development, January 11, 2000; 127(22): 4837 - 4843. [Abstract] [PDF]

				N Mercader, E Leonardo, M. Piedra, C Martinez-A, M. Ros, and M Torres Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes Development, January 9, 2000; 127(18): 3961 - 3970. [Abstract] [PDF]

				M Tanaka, M. Cohn, P Ashby, M Davey, P Martin, and C Tickle Distribution of polarizing activity and potential for limb formation in mouse and chick embryos and possible relationships to polydactyly Development, January 9, 2000; 127(18): 4011 - 4021. [Abstract] [PDF]

				C Hartmann and C. Tabin Dual roles of Wnt signaling during chondrogenesis in the chicken limb Development, January 7, 2000; 127(14): 3141 - 3159. [Abstract] [PDF]

				J Charite, D. McFadden, and E. Olson The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development Development, January 6, 2000; 127(11): 2461 - 2470. [Abstract] [PDF]

				L De Moerlooze, B Spencer-Dene, J Revest, M Hajihosseini, I Rosewell, and C Dickson An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis Development, January 2, 2000; 127(3): 483 - 492. [Abstract] [PDF]

				D. Garcia-Domingo, E. Leonardo, A. Grandien, P. Martinez, J. P. Albar, J. C. Izpisua-Belmonte, and C. Martinez-A DIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development PNAS, July 6, 1999; 96(14): 7992 - 7997. [Abstract] [Full Text] [PDF]

				M. Logan and C. J. Tabin Role of Pitx1 Upstream of Tbx4 in Specification of Hindlimb Identity Science, March 12, 1999; 283(5408): 1736 - 1739. [Abstract] [Full Text]