Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor

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				M. Hester, J. C. Thompson, J. Mills, Y. Liu, H. M. El-Hodiri, and M. Weinstein Smad1 and Smad8 Function Similarly in Mammalian Central Nervous System Development Mol. Cell. Biol., June 1, 2005; 25(11): 4683 - 4692. [Abstract] [Full Text] [PDF]

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				S Faure, M. Lee, T Keller, P ten Dijke, and M Whitman Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development Development, January 7, 2000; 127(13): 2917 - 2931. [Abstract] [PDF]

				K. Tremblay, P. Hoodless, E. Bikoff, and E. Robertson Formation of the definitive endoderm in mouse is a Smad2-dependent process Development, January 7, 2000; 127(14): 3079 - 3090. [Abstract] [PDF]

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				N. A. Armes, K. A. Neal, and J. C. Smith A Short Loop on the ALK-2 and ALK-4 Activin Receptors Regulates Signaling Specificity but Cannot Account for All Their Effects on Early Xenopus Development J. Biol. Chem., March 19, 1999; 274(12): 7929 - 7935. [Abstract] [Full Text] [PDF]

				T Ebisawa, K Tada, I Kitajima, K Tojo, T. Sampath, M Kawabata, K Miyazono, and T Imamura Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation J. Cell Sci., January 10, 1999; 112(20): 3519 - 3527. [Abstract] [PDF]

				M Hild, A Dick, G. Rauch, A Meier, T Bouwmeester, P Haffter, and M Hammerschmidt The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo Development, January 5, 1999; 126(10): 2149 - 2159. [Abstract] [PDF]

				J.-J. Lebrun, K. Takabe, Y. Chen, and W. Vale Roles of Pathway-Specific and Inhibitory Smads in Activin Receptor Signaling Mol. Endocrinol., January 1, 1999; 13(1): 15 - 23. [Abstract] [Full Text]

				M. Macias-Silva, P. A. Hoodless, S. J. Tang, M. Buchwald, and J. L. Wrana Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2 J. Biol. Chem., October 2, 1998; 273(40): 25628 - 25636. [Abstract] [Full Text] [PDF]

				P. E. Mead, Y. Zhou, K. D. Lustig, T. L. Huber, M. W. Kirschner, and L. I. Zon Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins PNAS, September 15, 1998; 95(19): 11251 - 11256. [Abstract] [Full Text] [PDF]

				Y.-G. Chen, A. Hata, R. S. Lo, D. Wotton, Y. Shi, N. Pavletich, and J. Massagué Determinants of specificity in TGF-beta signal�transduction Genes & Dev., July 15, 1998; 12(14): 2144 - 2152. [Abstract] [Full Text]

				K. Takeda, H. Ichijo, M. Fujii, Y. Mochida, M. Saitoh, H. Nishitoh, T. K. Sampath, and K. Miyazono Identification of a Novel Bone Morphogenetic Protein-responsive Gene That May Function as a Noncoding RNA J. Biol. Chem., July 3, 1998; 273(27): 17079 - 17085. [Abstract] [Full Text] [PDF]

				D. J. Crease, S. Dyson, and J. B. Gurdon Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression PNAS, April 14, 1998; 95(8): 4398 - 4403. [Abstract] [Full Text] [PDF]

				S. Zhou, P. Buckhaults, L. Zawel, F. Bunz, G. Riggins, J. Le Dai, S. E. Kern, K. W. Kinzler, and B. Vogelstein Targeted deletion of Smad4 shows it is required for transforming growth factor beta �and activin signaling in colorectal cancer cells PNAS, March 3, 1998; 95(5): 2412 - 2416. [Abstract] [Full Text] [PDF]

				A. Hata, G. Lagna, J. Massagué, and A. Hemmati-Brivanlou Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor�suppressor Genes & Dev., January 15, 1998; 12(2): 186 - 197. [Abstract] [Full Text]

				S. Tang, P. Hoodless, Z Lu, M. Breitman, R. McInnes, J. Wrana, and M Buchwald The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development Development, January 5, 1998; 125(10): 1877 - 1887. [Abstract] [PDF]

				J. Hudson, S. Podos, K Keith, S. Simpson, and E. Ferguson The Drosophila Medea gene is required downstream of dpp and encodes a functional homolog of human Smad4 Development, January 4, 1998; 125(8): 1407 - 1420. [Abstract] [PDF]

				T Nakayama, M. Snyder, S. Grewal, K Tsuneizumi, T Tabata, and J. Christian Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning Development, January 3, 1998; 125(5): 857 - 867. [Abstract] [PDF]

				C. Sirard, J. L. de la Pompa, A. Elia, A. Itie, C. Mirtsos, A. Cheung, S. Hahn, A. Wakeham, L. Schwartz, S. E. Kern, et al. The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse�embryo Genes & Dev., January 1, 1998; 12(1): 107 - 119. [Abstract] [Full Text]

				F. Liu, C. Pouponnot, and J. Massague Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta -inducible transcriptional�complexes Genes & Dev., December 1, 1997; 11(23): 3157 - 3167. [Abstract] [Full Text] [PDF]

				S. Abdollah, M. Macias-Silva, T. Tsukazaki, H. Hayashi, L. Attisano, and J. L. Wrana Tbeta RI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling J. Biol. Chem., October 31, 1997; 272(44): 27678 - 27685. [Abstract] [Full Text] [PDF]

				S. Souchelnytskyi, K. Tamaki, U. Engstrom, C. Wernstedt, P. ten Dijke, and C.-H. Heldin Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-beta Signaling J. Biol. Chem., October 31, 1997; 272(44): 28107 - 28115. [Abstract] [Full Text] [PDF]