Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival

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Articles by McMorris, F. A.

				S. L. Shankar, K. O'Guin, M. Kim, B. Varnum, G. Lemke, C. F. Brosnan, and B. Shafit-Zagardo Gas6/Axl Signaling Activates the Phosphatidylinositol 3-Kinase/Akt1 Survival Pathway to Protect Oligodendrocytes from Tumor Necrosis Factor{alpha}-Induced Apoptosis J. Neurosci., May 24, 2006; 26(21): 5638 - 5648. [Abstract] [Full Text] [PDF]

				R. D. McKinnon, S. Waldron, and M. E. Kiel PDGF {alpha}-Receptor Signal Strength Controls an RTK Rheostat That Integrates Phosphoinositol 3'-Kinase and Phospholipase C{gamma} Pathways during Oligodendrocyte Maturation J. Neurosci., April 6, 2005; 25(14): 3499 - 3508. [Abstract] [Full Text] [PDF]

				S. Subramaniam, N. Shahani, J. Strelau, C. Laliberte, R. Brandt, D. Kaplan, and K. Unsicker Insulin-Like Growth Factor 1 Inhibits Extracellular Signal-Regulated Kinase to Promote Neuronal Survival via the Phosphatidylinositol 3-Kinase/Protein Kinase A/c-Raf Pathway J. Neurosci., March 16, 2005; 25(11): 2838 - 2852. [Abstract] [Full Text] [PDF]

				Q.-L. Cui, W.-H. Zheng, R. Quirion, and G. Almazan Inhibition of Src-like Kinases Reveals Akt-dependent and -independent Pathways in Insulin-like Growth Factor I-mediated Oligodendrocyte Progenitor Survival J. Biol. Chem., March 11, 2005; 280(10): 8918 - 8928. [Abstract] [Full Text] [PDF]

				C. Jaillard, S. Harrison, B. Stankoff, M. S. Aigrot, A. R. Calver, G. Duddy, F. S. Walsh, M. N. Pangalos, N. Arimura, K. Kaibuchi, et al. Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival J. Neurosci., February 9, 2005; 25(6): 1459 - 1469. [Abstract] [Full Text] [PDF]

				Z. S. Boyd, A. Kriatchko, J. Yang, N. Agarwal, M. B. Wax, and R. V. Patil Interleukin-10 Receptor Signaling through STAT-3 Regulates the Apoptosis of Retinal Ganglion Cells in Response to Stress Invest. Ophthalmol. Vis. Sci., December 1, 2003; 44(12): 5206 - 5211. [Abstract] [Full Text] [PDF]

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				E. Molina-Holgado, J. M. Vela, A. Arevalo-Martin, G. Almazan, F. Molina-Holgado, J. Borrell, and C. Guaza Cannabinoids Promote Oligodendrocyte Progenitor Survival: Involvement of Cannabinoid Receptors and Phosphatidylinositol-3 Kinase/Akt Signaling J. Neurosci., November 15, 2002; 22(22): 9742 - 9753. [Abstract] [Full Text] [PDF]

				L. Soane, H.-J. Cho, F. Niculescu, H. Rus, and M. L. Shin C5b-9 Terminal Complement Complex Protects Oligodendrocytes from Death by Regulating Bad Through Phosphatidylinositol 3-Kinase/Akt Pathway J. Immunol., August 15, 2001; 167(4): 2305 - 2311. [Abstract] [Full Text] [PDF]

				B. R. Sperber, E. A. Boyle-Walsh, M. J. Engleka, P. Gadue, A. C. Peterson, P. L. Stein, S. S. Scherer, and F. A. McMorris A Unique Role for Fyn in CNS Myelination J. Neurosci., March 15, 2001; 21(6): 2039 - 2047. [Abstract] [Full Text] [PDF]

				O. Bang, E. Park, S. Yang, S. Lee, T. Franke, and S. Kang Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells J. Cell Sci., January 1, 2001; 114(1): 81 - 88. [Abstract] [PDF]

				A. I. Flores, B. S. Mallon, T. Matsui, W. Ogawa, A. Rosenzweig, T. Okamoto, and W. B. Macklin Akt-Mediated Survival of Oligodendrocytes Induced by Neuregulins J. Neurosci., October 15, 2000; 20(20): 7622 - 7630. [Abstract] [Full Text] [PDF]

				B. H. Han and D. M. Holtzman BDNF Protects the Neonatal Brain from Hypoxic-Ischemic Injury In Vivo via the ERK Pathway J. Neurosci., August 1, 2000; 20(15): 5775 - 5781. [Abstract] [Full Text] [PDF]

				P. Maurel and J. L. Salzer Axonal Regulation of Schwann Cell Proliferation and Survival and the Initial Events of Myelination Requires PI 3-Kinase Activity J. Neurosci., June 15, 2000; 20(12): 4635 - 4645. [Abstract] [Full Text] [PDF]

				M. A. Lawlor, X. Feng, D. R. Everding, K. Sieger, C. E. H. Stewart, and P. Rotwein Dual Control of Muscle Cell Survival by Distinct Growth Factor-Regulated Signaling Pathways Mol. Cell. Biol., May 1, 2000; 20(9): 3256 - 3265. [Abstract] [Full Text]

				C. L. Delaney and E. L. Feldman Review {blacksquare} : Insulin-like Growth Factor-I and Apoptosis in Glial Cell Biology Neuroscientist, February 1, 2000; 6(1): 39 - 47. [Abstract] [PDF]

				O. D. Slayden, J. S. Rubin, D. L. Lacey, and R. M. Brenner Effects of Keratinocyte Growth Factor in the Endometrium of Rhesus Macaques during the Luteal-Follicular Transition J. Clin. Endocrinol. Metab., January 1, 2000; 85(1): 275 - 285. [Abstract] [Full Text]

				S. R. Datta, A. Brunet, and M. E. Greenberg Cellular survival: a play in three Akts Genes & Dev., November 15, 1999; 13(22): 2905 - 2927. [Full Text]

				M. Hetman, K. Kanning, J. E. Cavanaugh, and Z. Xia Neuroprotection by Brain-derived Neurotrophic Factor Is Mediated by Extracellular Signal-regulated Kinase and Phosphatidylinositol 3-Kinase J. Biol. Chem., August 6, 1999; 274(32): 22569 - 22580. [Abstract] [Full Text] [PDF]

				J. Lin, R. M. Adam, E. Santiestevan, and M. R. Freeman The Phosphatidylinositol 3'-kinase Pathway Is a Dominant Growth Factor-activated Cell Survival Pathway in LNCaP Human Prostate Carcinoma Cells Cancer Res., June 1, 1999; 59(12): 2891 - 2897. [Abstract] [Full Text] [PDF]

				J. A. Weiner and J. Chun Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid PNAS, April 27, 1999; 96(9): 5233 - 5238. [Abstract] [Full Text] [PDF]

				M. A. Vogelbaum, J. X. Tong, and K. M. Rich Developmental Regulation of Apoptosis in Dorsal Root Ganglion Neurons J. Neurosci., November 1, 1998; 18(21): 8928 - 8935. [Abstract] [Full Text] [PDF]

				M. P. Scheid and V. Duronio Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: Involvement of MEK upstream of Bad phosphorylation PNAS, June 23, 1998; 95(13): 7439 - 7444. [Abstract] [Full Text] [PDF]

				R. M. Soler, J. Egea, G. M. Mintenig, C. Sanz-Rodriguez, M. Iglesias, and J. X. Comella Calmodulin Is Involved in Membrane Depolarization-Mediated Survival of Motoneurons by Phosphatidylinositol-3 Kinase- and MAPK-Independent Pathways J. Neurosci., February 15, 1998; 18(4): 1230 - 1239. [Abstract] [Full Text] [PDF]

				M. Holgado-Madruga, D. K. Moscatello, D. R. Emlet, R. Dieterich, and A. J. Wong Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth�factor PNAS, November 11, 1997; 94(23): 12419 - 12424. [Abstract] [Full Text] [PDF]

				K. L. Philpott, M. J. McCarthy, A. Klippel, and L. L. Rubin Activated Phosphatidylinositol 3-Kinase and Akt Kinase Promote Survival of Superior Cervical Neurons J. Cell Biol., November 3, 1997; 139(3): 809 - 815. [Abstract] [Full Text] [PDF]

				D. J. Creedon, M. G. Tansey, R. H. Baloh, P. A. Osborne, P. A. Lampe, T. J. Fahrner, R. O. Heuckeroth, J. Milbrandt, and E. M. Johnson Jr. Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic�neurons PNAS, June 24, 1997; 94(13): 7018 - 7023. [Abstract] [Full Text] [PDF]

				R. Takano, S. Hisahara, K. Namikawa, H. Kiyama, H. Okano, and M. Miura Nerve Growth Factor Protects Oligodendrocytes from Tumor Necrosis Factor-alpha -induced Injury through Akt-mediated Signaling Mechanisms J. Biol. Chem., May 19, 2000; 275(21): 16360 - 16365. [Abstract] [Full Text] [PDF]