spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jun, S.
Right arrow Articles by Desplan, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jun, S.
Right arrow Articles by Desplan, C.
Baldwin, C. T., Hoth, C. F., Amos, J. A., da Silva, E. and Milunsky, A (1992). An exonic mutation in the HuP2 paired domain gene causes Waardenburg's syndrome. Nature 355, 637-638.[Medline]

Bertuccioli, C., Fasano, L., Jun, S., Wang, S., Sheng, G. and Desplan, C (1996). In vivo requirement for the paired domain and homeodomain of the paired segmentation gene product. Development 122, 2673-2685.[Abstract]

Bopp, D., Burri, M., Baumgartner, S., Frigerio, G. and Noll, M (1986). Conservation of a large protein domain in the segmentation gene paired and in functionally related genes in Drosophila. Cell 47, 1033-1049.[Medline]

Cai, J., Lan, Y., Appel, L. F. and Weir, M (1994). Dissection of the Drosophila Paired protein: Functional requirements for conserved motifs. Mech. Dev 47, 139-150.[Medline]

Chalepakis, G., Fritsch, R., Fickenscher, H., Deutsch, U., Goulding, M. and Gruss, P (1991). The molecular basis of the undulated/Pax-1 mutation. Cell 66, 873-884.[Medline]

Chalepakis, G., Stoykova, A., Wijnholds, J., Tremblay, P. and Gruss, P (1993). Pax: gene regulators in the developing nervous system. J.Neurobiol 24, 1367-1384.[Medline]

Chan, S. K., Jaffe, L., Capovilla, M., Botas, J. and Mann, R. S (1994). The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein. Cell 78, 603-615.[Medline]

Chang, C., Shen, W., Rozenfeld, S., Lawrence, H. J., Largman, C. and Cleary, M. L (1995). Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev 9, 663-674.[Abstract/Free Full Text]

Chisholm, A. D. and Horvitz, H. R (1995). Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3. Nature 376, 52-55.

Cvekl, A., Sax, C. M., Li, X., McDermott, J. B. and Piatigorsky, J (1995). Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene. Proc. Natl. Acad. Sci. USA 92, 4681-4685.[Abstract/Free Full Text]

Czerny, T. and Busslinger, M (1995). DNA-binding and transactivation properties of Pax-6: three amino acids in the Paired Domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5). Molec. Cell. Biol 15, 2858-2871.[Abstract]

Czerny, T., Schaffner, G. and Busslinger, M (1993). DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev 7, 2048-2061.[Abstract/Free Full Text]

Ellenberger, T. E., Brandl, C. J., Struhl, K. and Harrison, S. C (1992). The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex. Cell 71, 1223-1237.[Medline]

Epstein, D. J., Malo, D., Vekemans, M. and Gros, P (1991). Molecular characterization of a deletion encompassing the splotch mutation on mouse chromosome 1. Genomics 10, 89-93.[Medline]

Epstein, D. J., Vekemans, M. and Gros, P (1991). splotch (Sp2H), a Mutation Affecting Development of the Mouse Neural Tube, Shows a Deletion within the Paired Homeodomain of Pax-3. Cell 67, 767-774.[Medline]

Epstein, J., Cai, J., Glaser, T., Jepeal, L. and Maas, R (1994). Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J. Biol. Chem 269, 8355-8361.[Abstract/Free Full Text]

Epstein, J. A., Glaser, T., Cai, J., Jepeal, L., Walton, D. S. and Maas, R. L (1994). Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev 8, 2022-2034.[Abstract/Free Full Text]

Fortini, M. E. and Rubin, G. M (1990). Analysis of cis-acting requirements of the Rh3 and Rh4 genes reveals a bipartite organization to rhodopsin promoters in Drosophila melanogaster. Genes Dev 4, 444-463.[Abstract/Free Full Text]

Frigerio, G., Burri, M., Bopp, D., Baumgartner, S. and Noll, M (1986). Structure of the segmentation of gene paired and the Drosophila PRD gene set as part of a gene network. Cell 47, 735-746.[Medline]

Fujioka, M., Miskiewicz, P., Raj, L., Gulledge, A., Weir M. and Goto, T (1996). Drosophila paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain. Development 122, 000-000.

Glaser, T., Walton, D. S. and Maas, R. L (1992). Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene. Nature Genetics 2, 232-239.[Medline]

Goulding, M., Sterrer, S., Fleming, J., Balling, R., Nadeau, J., Moore, K. J., Brown, S. D., Steel, K. P. and Gruss, P (1993). Analysis of the Pax-3 gene in the mouse mutant splotch. Genomics 17, 355-363.[Medline]

Halder, G., Callaerts, P. and Gehring, W. J (1995). Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila. Science 267, 1788-1792.[Abstract/Free Full Text]

Hanson, I. M., Fletcher, J. M., Jordan, T., Brown, A., Taylor, D., Adams, R. J., Punnett, H. H. and van Heyningen, H (1994). Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly. Nature Genetics 6, 168-173.[Medline]

Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D. and van Heyningen, H (1991). Mouse Small eye results from mutations in a paired-like homeobox-containing gene. Nature 354, 522-525.[Medline]

Jordan, T., Hanson, I., Zaletayev, D., Hodgson, S., Prosser, J., Seawright, A., Hastie, N. and van Heyningen, H (1992). The human PAX6 gene is mutated in two patients with aniridia. Nature Genetics 1, 328-332.[Medline]

Kilchherr, F., Baumgartern, S., Bopp, D., Frei, E. and Noll, A. M (1986). Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis. Nature 321, 493-499.

Klemm, J. D., Rould, M. A., Aurora, R., Herr, W. and Pabo, C. O (1994). Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77, 21-32.[Medline]

Luisi, B. F., Xu, W. X., Otwinowski, Z., Freedman, L. P., Yamamoto, K. R. and Sigler, P. B (1991). Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature 352, 497-505.[Medline]

Maulbecker, C. C. and Gruss, P (1993). The oncogenic potential of Pax genes. EMBO J 12, 2361-2367.[Medline]

Miller, J., McLachlan, A. D. and Klug, A (1985). Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J 4, 1609-1514.[Medline]

Miskiewicz, P., Morrissey, D., Lan, Y., Raj, L., Kessler, S., Fujioka, M., Goto, T. and Weir, M (1996). Both the paired domain and homeodomain are required for in vivo function of Drosophila Paired. Development 122, 2709-2718.[Abstract]

Mismer, D. and Rubin, G. M (1989). Definition of cis-acting elements regulating expression of the Drosophila melanogaster ninaE opsin gene by oligonucleotide-directed mutagenesis. Genetics 121, 77-87.[Abstract/Free Full Text]

Morell, R., Friedman, T. B., Moeljopawiro, S., Hartono, Soewito and Asher, J. J (1992). A frameshift mutation in the HuP2 paired domain of the probable human homolog of murine Pax-3 is responsible for Waardenburg syndrome type 1 in an Indonesian family. Human Molec. Genet 1, 243-247.[Abstract/Free Full Text]

Noll, M (1993). Evolution and role of Pax genes. Curr. Opin. Genet. Dev 3, 595-605.[Medline]

Pavletich, N. P. and Pabo, C. O (1993). Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. Science 261, 1701-1707.[Abstract/Free Full Text]

Quiring, R., Walldorf, U., Kloter, U. and Gehring, W. J (1994). Homology of the eyeless Gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265, 785-789.[Abstract/Free Full Text]

Rebar, E. J. and Pabo, C. O (1994). Zinc finger phage: affinity selection of fingers with new DNA-binding specificities. Science 263, 671-673.[Abstract/Free Full Text]

Richardson, J., Cvekl, A. and Wistow, G (1995). Pax-6 is essential for lens-specific expression of zeta-crystallin. Proc. Natl. Acad. Sci. USA 92, 4676-4680.[Abstract/Free Full Text]

Stapleton, P., Weith, A., Urbanek, P., Kozmik, Z. and Busslinger, M (1993). Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9. Nature Genetics 3, 292-298.[Medline]

Tassabehji, M., Read, A. P., Newton, V. E., Harris, R., Balling, R., Gruss, P. and Strachan, T (1992). Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene. Nature 355, 635-636.[Medline]

Treisman, J., Gonczy, P., Vashishtha, M., Harris, E. and Desplan, C (1989). A single amino acid can determine the DNA binding specificity of homeodomain proteins. Cell 59, 553-562.[Medline]

Treisman, J., Harris, E. and Desplan, C (1991). The Paired Box encodes a second DNA-binding domain in the Paired homeodomain protein. Genes Dev 5, 594-604.[Abstract/Free Full Text]

Tsukamoto, K., Nakamura, Y. and Niikawa, N (1994). Isolation of two isoforms of the PAX3 gene transcripts and their tissue-specific alternative expression in human adult tissues. Human Genet 93, 270-274.

van Dijk, M. A. and Murre, C (1994). Extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell 78, 617-624.[Medline]

Voronova, A. and Baltimore, D (1990). Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains. Proc. Natl. Acad. Sci. USA 87, 4722-4726.[Abstract/Free Full Text]

Wallin, J., Mizutani, Y., Imai, K., Miyashita, N., Moriwaki, K., Taniguchi, M., Koseki, H. and Balling, R (1993). A new Pax gene, Pax-9, maps to mouse chromosome 12. Mammalian Genome 4, 354-358.[Medline]

Walther, C., Guenet, J. L., Simon, D., Deutsch, U., Jostes, B., Goulding, M. D., Plachov, D., Balling, R. and Gruss, P (1991). Pax: a murine multigene family of paired box-containing genes. Genomics 11, 424-434.[Medline]

Wilson, D., Sheng, G., Lecuit, T., Dostatni, N. and Desplan, C (1993). Cooperative dimerization of paired class homeodomains on DNA. Genes Dev 7, 2120-2134.[Abstract/Free Full Text]

Wilson, D. S. and Desplan, C (1995). Homeodomain Proteins: Cooperating to be different. Current Biol 5, 32-34.[Medline]

Wilson, D. S., Guenther, B., Desplan, C. and Kuriyan, J (1995). High resolution crystal structure of a Paired (Pax) class cooperative homeodomain dimer on DNA. Cell 82, 709-719.[Medline]

Xu, W., Rould, M., Jun, S., Desplan, C. and Pabo, C (1995). Crystal structure of a paired domain-DNA complex at 2.5A resolution reveals structural basis for Pax developmental mutations. Cell 80, 639-650.[Medline]

Zhang, Y. and Emmons, S. W (1995). Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue. Nature 376, 55-59.




This article has been cited by other articles:


Home page
J. Biol. Chem.Home page
L. Codutti, H. van Ingen, C. Vascotto, F. Fogolari, A. Corazza, G. Tell, F. Quadrifoglio, P. Viglino, R. Boelens, and G. Esposito
The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family
J. Biol. Chem., November 28, 2008; 283(48): 33321 - 33328.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
N. Osumi, H. Shinohara, K. Numayama-Tsuruta, and M. Maekawa
Concise Review: Pax6 Transcription Factor Contributes to both Embryonic and Adult Neurogenesis as a Multifunctional Regulator
Stem Cells, July 1, 2008; 26(7): 1663 - 1672.
[Abstract] [Full Text] [PDF]


Home page
Hum Mol GenetHome page
G. N. Corry, M. J. Hendzel, and D. A. Underhill
Subnuclear localization and mobility are key indicators of PAX3 dysfunction in Waardenburg syndrome
Hum. Mol. Genet., June 15, 2008; 17(12): 1825 - 1837.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
E. A. Kim, Y. T. Noh, M.-J. Ryu, H.-T. Kim, S.-E. Lee, C.-H. Kim, C. Lee, Y. H. Kim, and C. Y. Choi
Phosphorylation and Transactivation of Pax6 by Homeodomain-interacting Protein Kinase 2
J. Biol. Chem., March 17, 2006; 281(11): 7489 - 7497.
[Abstract] [Full Text] [PDF]


Home page
Nucleic Acids ResHome page
C. Feschotte, M. T. Osterlund, R. Peeler, and S. R. Wessler
DNA-binding specificity of rice mariner-like transposases and interactions with Stowaway MITEs
Nucleic Acids Res., April 14, 2005; 33(7): 2153 - 2165.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
N. Haubst, J. Berger, V. Radjendirane, J. Graw, J. Favor, G. F. Saunders, A. Stoykova, and M. Gotz
Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development
Development, December 15, 2004; 131(24): 6131 - 6140.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
L. Leconte, L. Lecoin, P. Martin, and S. Saule
Pax6 Interacts with cVax and Tbx5 to Establish the Dorsoventral Boundary of the Developing Eye
J. Biol. Chem., November 5, 2004; 279(45): 47272 - 47277.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
C. C. Martin, J. K. Oeser, and R. M. O'Brien
Differential Regulation of Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein Gene Transcription by Pax-6 and Pdx-1
J. Biol. Chem., August 13, 2004; 279(33): 34277 - 34289.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Apuzzo, A. Abdelhakim, A. S. Fortin, and P. Gros
Cross-talk between the Paired Domain and the Homeodomain of Pax3: DNA BINDING BY EACH DOMAIN CAUSES A STRUCTURAL CHANGE IN THE OTHER DOMAIN, SUPPORTING INTERDEPENDENCE FOR DNA BINDING
J. Biol. Chem., August 6, 2004; 279(32): 33601 - 33612.
[Abstract] [Full Text] [PDF]


Home page
Nucleic Acids ResHome page
B. K. Chauhan, Y. Yang, K. Cveklova, and A. Cvekl
Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency
Nucleic Acids Res., March 12, 2004; 32(5): 1696 - 1709.
[Abstract] [Full Text] [PDF]


Home page
IOVSHome page
B. K. Chauhan, Y. Yang, K. Cveklova, and A. Cvekl
Functional Properties of Natural Human PAX6 and PAX6(5a) Mutants
Invest. Ophthalmol. Vis. Sci., February 1, 2004; 45(2): 385 - 392.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
S. Aldaz, G. Morata, and N. Azpiazu
The Pax-homeobox gene eyegone is involved in the subdivision of the thorax of Drosophila
Development, September 15, 2003; 130(18): 4473 - 4482.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C.-C. Jang, J.-L. Chao, N. Jones, L.-C. Yao, D. A. Bessarab, Y. M. Kuo, S. Jun, C. Desplan, S. K. Beckendorf, and Y. H. Sun
Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development
Development, July 1, 2003; 130(13): 2939 - 2951.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
D. A. Tyas, H. Pearson, P. Rashbass, and D. J. Price
Pax6 Regulates Cell Adhesion during Cortical Development
Cereb Cortex, June 1, 2003; 13(6): 612 - 619.
[Abstract] [Full Text] [PDF]


Home page
Hum Mol GenetHome page
D. Lang and J. A. Epstein
Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer
Hum. Mol. Genet., April 15, 2003; 12(8): 937 - 945.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C. Benassayag, S. Plaza, P. Callaerts, J. Clements, Y. Romeo, W. J. Gehring, and D. L. Cribbs
Evidence for a direct functional antagonism of the selector genes proboscipedia and eyeless in Drosophila head development
Development, February 1, 2003; 130(3): 575 - 586.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
H. Skala-Rubinson, J. Vinh, V. Labas, A. Kahn, and F. P. D. Tuy
Novel Target Sequences for Pax-6 in the Brain-specific Activating Regions of the Rat Aldolase C Gene
J. Biol. Chem., November 27, 2002; 277(49): 47190 - 47196.
[Abstract] [Full Text] [PDF]


Home page
Genome ResHome page
Y.-H. Zhou, J. B. Zheng, X. Gu, G. F. Saunders, and W.-K. A. Yung
Novel PAX6 Binding Sites in the Human Genome and the Role of Repetitive Elements in the Evolution of Gene Regulation
Genome Res., November 1, 2002; 12(11): 1716 - 1722.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
Z. Izsvak, D. Khare, J. Behlke, U. Heinemann, R. H. Plasterk, and Z. Ivics
Involvement of a Bifunctional, Paired-like DNA-binding Domain and a Transpositional Enhancer in Sleeping Beauty Transposition
J. Biol. Chem., September 6, 2002; 277(37): 34581 - 34588.
[Abstract] [Full Text] [PDF]


Home page
Mol Biol EvolHome page
H. Sun, S. Merugu, X. Gu, Y. Y. Kang, D. P. Dickinson, P. Callaerts, and W.-H. Li
Identification of Essential Amino Acid Changes in Paired Domain Evolution Using a Novel Combination of Evolutionary Analysis and In Vitro and In Vivo Studies
Mol. Biol. Evol., September 1, 2002; 19(9): 1490 - 1500.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
S. Singh, R. Mishra, N. A. Arango, J. M. Deng, R. R. Behringer, and G. F. Saunders
Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform
PNAS, May 14, 2002; 99(10): 6812 - 6815.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
B. K. Chauhan, N. A. Reed, W. Zhang, M. K. Duncan, M. W. Kilimann, and A. Cvekl
Identification of Genes Downstream of Pax6 in the Mouse Lens Using cDNA Microarrays
J. Biol. Chem., March 22, 2002; 277(13): 11539 - 11548.
[Abstract] [Full Text] [PDF]


Home page
Mol Biol EvolHome page
H. Sun, D. P. Dickinson, J. Costello, and W.-H. Li
Isolation of Cladonema Pax-B Genes and Studies of the DNA-Binding Properties of Cnidarian Pax Paired Domains
Mol. Biol. Evol., October 1, 2001; 18(10): 1905 - 1918.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
C. Punzo, S. Kurata, and W. J. Gehring
The eyeless homeodomain is dispensable for eye development in Drosophila
Genes & Dev., July 1, 2001; 15(13): 1716 - 1723.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
L Xue, X Li, and M Noll
Multiple protein functions of paired in Drosophila development and their conservation in the Gooseberry and Pax3 homologs
Development, January 2, 2001; 128(3): 395 - 405.
[Abstract] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
C. Vilain, C. Rydlewski, L. Duprez, C. Heinrichs, M. Abramowicz, P. Malvaux, B. Renneboog, J. Parma, S. Costagliola, and G. Vassart
Autosomal Dominant Transmission of Congenital Thyroid Hypoplasia Due to Loss-of-Function Mutation of PAX8
J. Clin. Endocrinol. Metab., January 1, 2001; 86(1): 234 - 238.
[Abstract] [Full Text]


Home page
Nucleic Acids ResHome page
M. S. Lechner, I. Levitan, and G. R. Dressler
PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin
Nucleic Acids Res., July 15, 2000; 28(14): 2741 - 2751.
[Abstract] [Full Text] [PDF]


Home page
Nucleic Acids ResHome page
A. Carr and M. D. Biggin
Accessibility of transcriptionally inactive genes is specifically reduced at homeoprotein-DNA binding sites in Drosophila
Nucleic Acids Res., July 15, 2000; 28(14): 2839 - 2846.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
D. J. Miller, D. C. Hayward, J. S. Reece-Hoyes, I. Scholten, J. Catmull, W. J. Gehring, P. Callaerts, J. E. Larsen, and E. E. Ball
Special Feature: Pax gene diversity in the basal cnidarian Acropora millepora (Cnidaria, Anthozoa): Implications for the evolution of the Pax gene family
PNAS, April 25, 2000; 97(9): 4475 - 4480.
[Abstract] [Full Text] [PDF]


Home page
IOVSHome page
M. K. Duncan, A. Cvekl, X. Li, and J. Piatigorsky
Truncated Forms of Pax-6 Disrupt Lens Morphology in Transgenic Mice
Invest. Ophthalmol. Vis. Sci., February 1, 2000; 41(2): 464 - 473.
[Abstract] [Full Text]


Home page
J. Cell Sci.Home page
M. Duncan, Z Kozmik, K Cveklova, J Piatigorsky, and A Cvekl
Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression
J. Cell Sci., January 9, 2000; 113(18): 3173 - 3185.
[Abstract] [PDF]


Home page
Mol. Cell. Biol.Home page
S. B. Smith, H. C. Ee, J. R. Conners, and M. S. German
Paired-Homeodomain Transcription Factor PAX4 Acts as a Transcriptional Repressor in Early Pancreatic Development
Mol. Cell. Biol., December 1, 1999; 19(12): 8272 - 8280.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
Y. Fujitani, Y. Kajimoto, T. Yasuda, T.-A. Matsuoka, H. Kaneto, Y. Umayahara, N. Fujita, H. Watada, J.-I. Miyazaki, Y. Yamasaki, et al.
Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas
Mol. Cell. Biol., December 1, 1999; 19(12): 8281 - 8291.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M.-D. Galibert, U. Yavuzer, T. J. Dexter, and C. R. Goding
Pax3 and Regulation of the Melanocyte-specific Tyrosinase-related Protein-1 Promoter
J. Biol. Chem., September 17, 1999; 274(38): 26894 - 26900.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
H. E. Xu, M. A. Rould, W. Xu, J. A. Epstein, R. L. Maas, and C. O. Pabo
Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding
Genes & Dev., May 15, 1999; 13(10): 1263 - 1275.
[Abstract] [Full Text]


Home page
Proc. Natl. Acad. Sci. USAHome page
S. Jun, R. V. Wallen, A. Goriely, B. Kalionis, and C. Desplan
Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition
PNAS, November 10, 1998; 95(23): 13720 - 13725.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
G. Tell, A. Scaloni, L. Pellizzari, S. Formisano, C. Pucillo, and G. Damante
Redox Potential Controls the Structure and DNA Binding Activity of the Paired Domain
J. Biol. Chem., September 25, 1998; 273(39): 25062 - 25072.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
M. K. Duncan, J. I. Haynes II, A. Cvekl, and J. Piatigorsky
Dual Roles for Pax-6: a Transcriptional Repressor of Lens Fiber Cell-Specific beta -Crystallin Genes
Mol. Cell. Biol., September 1, 1998; 18(9): 5579 - 5586.
[Abstract] [Full Text]


Home page
J. Biol. Chem.Home page
S. A. Phelan and M. R. Loeken
Identification of a New Binding Motif for the Paired Domain of Pax-3 and Unusual Characteristics of Spacing of Bipartite Recognition Elements on Binding and Transcription Activation
J. Biol. Chem., July 24, 1998; 273(30): 19153 - 19159.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
R. Sharon-Friling, J. Richardson, S. Sperbeck, D. Lee, M. Rauchman, R. Maas, A. Swaroop, and G. Wistow
Lens-Specific Gene Recruitment of zeta -Crystallin through Pax6, Nrl-Maf, and Brain Suppressor Sites
Mol. Cell. Biol., April 1, 1998; 18(4): 2067 - 2076.
[Abstract] [Full Text]


Home page
DevelopmentHome page
N. Jones, Y. Kuo, Y. Sun, and S. Beckendorf
The Drosophila Pax gene eye gone is required for embryonic salivary duct development
Development, January 11, 1998; 125(21): 4163 - 4174.
[Abstract] [PDF]


Home page
DevelopmentHome page
D. Hazelett, M Bourouis, U Walldorf, and J. Treisman
decapentaplegic and wingless are regulated by eyes absent and eyegone and interact to direct the pattern of retinal differentiation in the eye disc
Development, January 9, 1998; 125(18): 3741 - 3751.
[Abstract] [PDF]


Home page
J. Biol. Chem.Home page
G. C. Fraizer, R. Shimamura, X. Zhang, and G. F. Saunders
PAX 8 Regulates Human WT1 Transcription through a Novel DNA Binding Site
J. Biol. Chem., December 5, 1997; 272(49): 30678 - 30687.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. J. Vogan and P. Gros
The C-terminal Subdomain Makes an Important Contribution to the DNA Binding Activity of the Pax-3 Paired Domain
J. Biol. Chem., November 7, 1997; 272(45): 28289 - 28295.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. A. Underhill and P. Gros
The Paired-domain Regulates DNA Binding by the Homeodomain within the Intact Pax-3 Protein
J. Biol. Chem., May 30, 1997; 272(22): 14175 - 14182.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
G Sheng, E Thouvenot, D Schmucker, D S Wilson, and C Desplan
Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors.
Genes & Dev., May 1, 1997; 11(9): 1122 - 1131.
[Abstract] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
B. D. Holst, Y. Wang, F. S. Jones, and G. M. Edelman
A binding site for Pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord
PNAS, February 18, 1997; 94(4): 1465 - 1470.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
K. Ren, E. M. Blass, Q.-q. Zhou, and R. Dubner
Suckling and sucrose ingestion suppress persistent hyperalgesia and spinal Fos expression after forepaw inflammation in infant rats
PNAS, February 18, 1997; 94(4): 1471 - 1475.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
H. Chamberlin, R. Palmer, A. Newman, P. Sternberg, D. Baillie, and J. Thomas
The PAX gene egl-38 mediates developmental patterning in Caenorhabditis elegans
Development, January 10, 1997; 124(20): 3919 - 3928.
[Abstract] [PDF]


Home page
DevelopmentHome page
C Bertuccioli, L Fasano, S Jun, S Wang, G Sheng, and C Desplan
In vivo requirement for the paired domain and homeodomain of the paired segmentation gene product
Development, January 9, 1996; 122(9): 2673 - 2685.
[Abstract] [PDF]


Home page
DevelopmentHome page
M Fujioka, P Miskiewicz, L Raj, A. Gulledge, M Weir, and T Goto
Drosophila Paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain
Development, January 9, 1996; 122(9): 2697 - 2707.
[Abstract] [PDF]


Home page
DevelopmentHome page
P Miskiewicz, D Morrissey, Y Lan, L Raj, S Kessler, M Fujioka, T Goto, and M Weir
Both the paired domain and homeodomain are required for in vivo function of Drosophila Paired
Development, January 9, 1996; 122(9): 2709 - 2718.
[Abstract] [PDF]


Home page
J. Biol. Chem.Home page
S. Singh, C. M. Stellrecht, H. K. Tang, and G. F. Saunders
Modulation of PAX6 Homeodomain Function by the Paired Domain
J. Biol. Chem., June 2, 2000; 275(23): 17306 - 17313.
[Abstract] [Full Text] [PDF]